In this review article we examine the role of glutathione reductase in the regulation,
modulation and maintenance of cellular redox homoeostasis. Glutathione reductase is …

All pharmaceutical products contain organic molecules; the source may be a natural product
or a fully synthetic molecule, or a combination of both. Thus, it follows that organic chemistry …

The global challenge to the treatment of malaria is mainly the occurrence of resistance of
malaria parasites to conventionally used antimalarials. Artesunate, a semisynthetic …

Tafenoquine is an 8-aminoquinoline with activity against all human life cycle stages of
Plasmodium vivax, including dormant liver stages–so called hypnozoites. Its long half-life …

Optic neuropathies are an important cause of blindness worldwide. The study of the most
common inherited mitochondrial optic neuropathies, Leber hereditary optic neuropathy …

Background Artemisinin-based combination therapies (ACTs) are the recommended first-
line treatment for uncomplicated Plasmodium falciparum malaria. Ferroquine is a new …

Background Cipargamin (KAE609) is a novel spiroindolone class drug for the treatment of
malaria, currently undergoing phase 2 clinical development. This review provides an …

Although malaria remains a big burden to many countries that it threatens their socio-
economic stability, particularly in the countries where malaria is endemic, there have been …

The review deals with the pharmaceutically and agrochemically important group of 1, 2, 4-
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …

The scientific community worldwide has realized that malaria elimination will not be possible
without development of safe and effective transmission-blocking interventions. Primaquine …