Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Vimentin as a potential target for diverse nervous system diseases

KZ Chen, SX Liu, YW Li, T He, J Zhao… - Neural regeneration …, 2023 - journals.lww.com
Vimentin is a major type III intermediate filament protein that plays important roles in several
basic cellular functions including cell migration, proliferation, and division. Although vimentin …

Immaturity of immune cells around the dural venous sinuses contributes to viral meningoencephalitis in neonates

YC Kim, JH Ahn, H Jin, MJ Yang, SP Hong… - Science …, 2023 - science.org
High neonatal susceptibility to meningitis has been attributed to the anatomical barriers that
act to protect the central nervous system (CNS) from infection being immature and not fully …

Formation and function of the meningeal arachnoid barrier around the developing mouse brain

J Derk, CN Como, HE Jones, LR Joyce, S Kim… - Developmental cell, 2023 - cell.com
The arachnoid barrier, a component of the blood-cerebrospinal fluid barrier (B-CSFB) in the
meninges, is composed of epithelial-like, tight-junction-expressing cells. Unlike other central …

[HTML][HTML] The communication mechanism of the gut-brain axis and its effect on central nervous system diseases: A systematic review

S Lu, Q Zhao, Y Guan, Z Sun, W Li, S Guo… - Biomedicine & …, 2024 - Elsevier
Gut microbiota is involved in intricate and active metabolic processes the host's brain
function, especially its role in immune responses, secondary metabolism, and symbiotic …

Microbiota–gut–brain axis: interplay between microbiota, barrier function and lymphatic system

M Zhuang, X Zhang, J Cai - Gut Microbes, 2024 - Taylor & Francis
The human gastrointestinal tract, boasting the most diverse microbial community, harbors
approximately 100 trillion microorganisms comprising viruses, bacteria, fungi, and archaea …

[HTML][HTML] Role of the gut-microbiota-metabolite-brain axis in the pathogenesis of preterm brain injury

L Li, J Yang, T Liu, Y Shi - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Brain injury, a common complication in preterm infants, includes the destruction of the key
structural and functional connections of the brain and causes neurodevelopmental …

Neonatal intestinal colonization of Streptococcus agalactiae and the multiple modes of protection limiting translocation

KG Greenfield, OS Harlow, LT Witt, EM Dziekan… - Gut …, 2024 - Taylor & Francis
Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is a predominant
pathogen of neonatal sepsis, commonly associated with early-onset neonatal sepsis. GBS …

Interspecies Interactions within the Host: the Social Network of Group B Streptococcus

ME Mejia, CM Robertson, KA Patras - Infection and Immunity, 2023 - Am Soc Microbiol
ABSTRACT Group B Streptococcus (GBS) is a pervasive neonatal pathogen accounting for
a combined half a million deaths and stillbirths annually. The most common source of fetal or …

Clonal and Horizontal Transmission of blaNDM among Klebsiella pneumoniae in Children's Intensive Care Units

B Fu, D Yin, C Sun, Y Shen, D Liu, R Bai… - Microbiology …, 2022 - Am Soc Microbiol
Increasing infections caused by bla NDM-carrying Klebsiella pneumoniae (NDM-KP) are an
urgent threat to children with weakened immunity and limited antibiotic use. Preventing and …