Another renaissance for bile acid gastrointestinal microbiology

JM Ridlon, HR Gaskins - Nature Reviews Gastroenterology & …, 2024 - nature.com
The field of bile acid microbiology in the gastrointestinal tract is going through a current
rebirth after a peak of activity in the late 1970s and early 1980s. This renewed activity is a …

The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract

O Perdijk, R Azzoni, BJ Marsland - Physiological Reviews, 2024 - journals.physiology.org
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community

AS Weiss, LS Niedermeier, A von Strempel… - Nature …, 2023 - nature.com
A challenging task to understand health and disease-related microbiome signatures is to
move beyond descriptive community-level profiling towards disentangling microbial …

Psychological stress-induced microbial metabolite indole-3-acetate disrupts intestinal cell lineage commitment

W Wei, Y Liu, Y Hou, S Cao, Z Chen, Y Zhang, X Cai… - Cell Metabolism, 2024 - cell.com
The brain and gut are intricately connected and respond to various stimuli. Stress-induced
brain-gut communication is implicated in the pathogenesis and relapse of gut disorders. The …

Phylogenetic distribution and experimental characterization of corrinoid production and dependence in soil bacterial isolates

ZI Alvarez-Aponte, AM Govindaraju… - The ISME …, 2024 - academic.oup.com
Soil microbial communities impact carbon sequestration and release, biogeochemical
cycling, and agricultural yields. These global effects rely on metabolic interactions that …

Strategies for tailoring functional microbial synthetic communities

J Jing, P Garbeva, JM Raaijmakers… - The ISME …, 2024 - academic.oup.com
Natural ecosystems harbor a huge reservoir of taxonomically diverse microbes that are
important for plant growth and health. The vast diversity of soil microorganisms and their …

Eco-evolutionary feedbacks in the human gut microbiome

BH Good, LB Rosenfeld - Nature Communications, 2023 - nature.com
Gut microbiota can evolve within their hosts on human-relevant timescales, but little is
known about how these changes influence (or are influenced by) the composition of their …

Bile acids impact the microbiota, host, and C. difficile dynamics providing insight into mechanisms of efficacy of FMTs and microbiota-focused therapeutics

AS McMillan, CM Theriot - Gut Microbes, 2024 - Taylor & Francis
Clostridioides difficile is a major nosocomial pathogen, causing significant morbidity and
mortality worldwide. Antibiotic usage, a major risk factor for Clostridioides difficile infection …

Spatial analysis of murine microbiota and bile acid metabolism during amoxicillin treatment

CN Beekman, S Penumutchu, R Peterson, G Han… - Cell Reports, 2024 - cell.com
Antibiotics cause collateral damage to resident microbes that is associated with various
health risks. To date, studies have largely focused on the impacts of antibiotics on large …

Design and analysis of quorum sensing language “Interpreter” ecosystem for microbial community

S Wu, H Zhang, Y Zhou, C Xu, B Yuan, H Wang… - Chemical Engineering …, 2024 - Elsevier
Microbes in diverse natural communities communicate via quorum sensing (QS) signals that
act as microbial languages. QS-based communications have been reconstructed in two …