Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a
dismal prognosis. The current mainstay of treatment involves maximally safe surgical …

Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60–
90%. HCMV is the leading cause of congenital infections and poses a great health risk to …

Glioblastoma multiforme (GBM) is one of the most aggressive human brain malignancies.
Even with optimal treatment, median survival is less than 6 months for patients with recurrent …

Human cytomegalovirus (HCMV) exhibits surprisingly high genomic diversity during natural
infection although little is known about the limits or patterns of HCMV diversity among …

Populations of human cytomegalovirus (HCMV), a large DNA virus, are highly polymorphic
in patient samples, which may allow for rapid evolution within human hosts. To understand …

Cytomegalovirus is highly prevalent in glioblastomas. In 2006, we initiated a randomized,
double‐blind, placebo‐controlled, hypothesis‐generating study to examine the safety and …

It is well-established that infections with viruses harboring oncogenic potential increase the
cancer risk. Virus induced oncogenic processes are influenced by a complex and unique …

Cytomegalovirus (CMV) has been implicated in glioblastoma (GBM); however, a
mechanistic connection in vivo has not been established. The purpose of this study is to …

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with an
extremely poor prognosis. There is a dire need to develop effective therapeutics to …

Herpesviruses encode membrane-associated G protein-coupled receptors (GPCRs) in their
viral genomes that are structurally similar to chemokine receptors. These GPCRs hijack …