Endolysins are bacteriophage-encoded enzymes that can specifically degrade the
peptidoglycan layer of bacterial cell wall, making them an attractive tool for the development …

Holins are bacteriophage-encoded transmembrane proteins that function to control the
timing of bacterial lysis event, assist with the destabilization of the membrane proton motive …

ABSTRACT The Virus-X—Viral Metagenomics for Innovation Value—project was a scientific
expedition to explore and exploit uncharted territory of genetic diversity in extreme natural …

Antimicrobial peptides (AMPs) are natural compounds that exhibit potent antimicrobial
activity against various microorganisms, including bacteria, fungi, and viruses. However, the …

This work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30),
which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide …

Phage-encoded endolysins are emerging antibacterial agents based on their ability to
efficiently degrade peptidoglycan on Gram-positive bacteria, but the envelope …

Aeromonas veronii is one of the predominant pathogenic species that can imperil the
survival of farmed fish. However, the interactive networks of immune regulation and …

The search for new microbicide compounds is of an urgent need, especially against difficult-
to-eradicate biofilm-forming bacteria. One attractive option is the application of cationic …

The ability to form robust biofilms and secrete a diverse array of virulence factors are key
pathogenic determinants of Staphylococcus aureus, causing a wide range of infectious …

Introduction In the era of increasing bacterial resistance to antibiotics, new bactericidal
substances are sought, and lysins derived from extremophilic organisms have the …