Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and
mechanical properties, which makes it well-suited for several engineering applications. Due …

One of the most popular methods to fabricate biomedical microfluidic devices is by using a
soft-lithography technique. However, the fabrication of the moulds to produce microfluidic …

Since the first microfluidic device was developed more than three decades ago, microfluidics
is seen as a technology that exhibits unique features to provide a significant change in the …

It is well known that certain pathological conditions result in a decrease of red blood cells
(RBCs) deformability and subsequently can significantly alter the blood flow in …

This review examines the state of the art for manufacturing non-planar miniature channels
and actuators from PDMS, where non-planar structures are defined here as those beyond …

Microvascular networks feature a complex topology with multiple bifurcating vessels.
Nonuniform partitioning (phase separation) of red blood cells (RBCs) occurs at diverging …

In microcirculation, red blood cells (RBCs) flowing through bifurcations may deform
considerably due to combination of different phenomena that happen at the micro-scale …

Microfluidic devices are electrical/mechanical systems that offer the ability to work with
minimal sample volumes, short reactions times, and have the possibility to perform massive …

Polydimethylsiloxane (PDMS) is a bioinert synthetic polymer with tunable elastic properties
that is commonly used as a cell culture substrate. Although plasma treatments are widely …

Over the years, various experimental methods have been applied in an effort to understand
the blood flow behavior in microcirculation. Most of our current knowledge in …