The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

[HTML][HTML] Adiponectin in insulin resistance: lessons from translational research

F Ziemke, CS Mantzoros - The American journal of clinical nutrition, 2010 - Elsevier
Adiponectin is an adipose tissue–secreted endogenous insulin sensitizer, which plays a key
role as a mediator of peroxisome proliferator-activated receptor γ action. Adiponectin alters …

Adiponectin and cancer: a systematic review

I Kelesidis, T Kelesidis, CS Mantzoros - British journal of cancer, 2006 - nature.com
Recent studies have demonstrated that obesity is a significant risk factor for the development
of several malignancies, but the mechanisms underlying this relationship remain to be fully …

Targeting signal‐transducer‐and‐activator‐of‐transcription‐3 for prevention and therapy of cancer: modern target but ancient solution

BB Aggarwal, G Sethi, KS Ahn… - Annals of the New …, 2006 - Wiley Online Library
Recent evidence indicates a convergence of molecular targets for both prevention and
therapy of cancer. Signal‐transducer‐and‐activator‐of‐transcription‐3 (STAT3), a member …

Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cells

MN Dieudonne, M Bussiere, E Dos Santos… - Biochemical and …, 2006 - Elsevier
It is well established that obesity is a risk factor for breast cancer and that blood levels of
adiponectin, a hormone mainly secreted by white adipocytes, are inversely correlated with …

[HTML][HTML] Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence

D Barb, CJ Williams, AK Neuwirth… - The American journal of …, 2007 - Elsevier
Adiponectin, an adipocyte-secreted hormone that plays an important role in diabetes and
cardiovascular disease, may also be of importance in the development and progression of …

Role of leptin and adiponectin in endometrial cancer

A Słabuszewska-Jóźwiak, A Lukaszuk… - International journal of …, 2022 - mdpi.com
Endometrial cancer is the most common malignancy of the female genital tract. Obesity is a
strong risk factor for endometrial cancer. Adipose tissue is an active endocrine organ that …

Adiponectin induces TNF-α and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli

C Tsatsanis, V Zacharioudaki, A Androulidaki… - Biochemical and …, 2005 - Elsevier
Adiponectin exerts anti-inflammatory effects via macrophages, suppressing the production of
pro-inflammatory cytokines in response to bacterial lipopolysaccharide (LPS). Here, we …

Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen …

A Koskinen, S Juslin, R Nieminen, T Moilanen… - Arthritis research & …, 2011 - Springer
Introduction Adiponectin is an adipokine that regulates energy metabolism and insulin
sensitivity, but recent studies have pointed also to a role in inflammation and arthritis. The …

Adiponectin as a growth inhibitor in prostate cancer cells

JD Bub, T Miyazaki, Y Iwamoto - Biochemical and biophysical research …, 2006 - Elsevier
Prostate cancer is associated with obesity. However, the molecular basis of this association
is not well known. Adiponectin is a major adipose cytokine that decreases in circulation in …