Aberrant gene silencing is highly associated with altered cell cycle regulation during
carcinogenesis. In particular, silencing of the CDKN2A tumor suppressor gene, which …

Head and neck cancer (HNC) broadly includes carcinomas arising from the mucosal
epithelia of the head and neck region as well as various cell types of salivary glands and the …

Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

To more fully characterize the clinical and pathologic spectrum of a recently described tumor
entity of the sinonasal tract characterized by loss of nuclear expression of SMARCB1 (INI1) …

Abstract The World Health Organization Classification of Head and Neck Tumours recently
published the 5th edition. There are new entities, emerging entities, and significant updates …

The sinonasal cavities represent an anatomical region affected by a variety of tumours with
clinical, aetiological, pathological, and genetic features distinct from tumours at the main …

Human papillomavirus (HPV)–related multiphenotypic sinonasal carcinoma (HMSC),
originally known as HPV-related carcinoma with adenoid cystic carcinoma-like features, is a …

High-risk human papillomavirus (HPV) positive squamous cell carcinoma (SCC) of the head
and neck is reported most commonly in the oropharynx but can also uncommonly be found …

Background To determine genomic alterations in head and neck squamous cell carcinoma
(HNSCC) using formalin-fixed, paraffin-embedded (FFPE) tumors obtained through routine …