Molecular and regulatory mechanisms of oxidative stress adaptation in Streptococcus mutans

S Yu, Q Ma, Y Li, J Zou - Molecular Oral Microbiology, 2023 - Wiley Online Library
Dental caries is a chronic progressive disease, which destructs dental hard tissues under
the influence of multiple factors, mainly bacteria. Streptococcus mutans is the main …

Oxidative stress response: a critical factor affecting the ecological competitiveness of Streptococcus mutans

X Cheng, X Xu, X Zhou, J Ning - Journal of Oral Microbiology, 2024 - Taylor & Francis
Oral microecological balance is closely associated with the development of dental caries.
Oxidative stress is one of the important factors regulating the composition and structure of …

Human saliva modifies growth, biofilm architecture, and competitive behaviors of oral streptococci

A Choi, K Dong, E Williams, L Pia, J Batagower… - Msphere, 2024 - Am Soc Microbiol
The bacteria within supragingival biofilms participate in complex exchanges with other
microbes inhabiting the same niche. One example is the mutans group streptococci …

PerR-regulated manganese import contributes to oxidative stress defense in Streptococcus suis

W Peng, X Yang, N Wang, T Gao, Z Liu… - Applied and …, 2022 - Am Soc Microbiol
Streptococcus suis has been increasingly recognized as a porcine zoonotic pathogen that
threatens the health of both pigs and humans. Metal homeostasis plays a critical role in the …

LiaSR two-component system modulates the oxidative stress response in Streptococcus mutans

S Huang, J Du, Y Li, M Wu, S Chen, S Jiang… - Microbial …, 2023 - Elsevier
Many commensal bacteria of the human oral microbiome can produce reactive oxygen
species (ROS). ROS will inhibit the colonization of Streptococcus mutans (S. mutans), a …

Deciphering the contribution of PerR to oxidative stress defense system in Clostridium tyrobutyricum

L Yang, Z Yang, J Liu, Z Liu, Y Liu, L Zhu, Z Zhu… - Food …, 2023 - Wiley Online Library
As a next‐generation probiotic, Clostridium tyrobutyricum, which is considered obligate
anaerobe, has been extensively considered a promising candidate for future use to promote …

Multiple factors regulate the expression of sufCDSUB in Streptococcus mutans

K Ellepola, LC Guillot, B Comeaux, Y Han… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction The sufCDSUB gene cluster, encoding the sole iron-sulfur (Fe-S) cluster
assembly system in S. mutans, was recently shown to be up-regulated in response to …

Small regulatory RNAs are mediators of the Streptococcus mutans SloR regulon

IY Drummond, A DePaolo, M Krieger… - Journal of …, 2023 - Am Soc Microbiol
Dental caries is among the most prevalent chronic diseases worldwide. Streptococcus
mutans, the chief causative agent of caries, uses a 25-kDa manganese-dependent SloR …

Biofilm formation on glycated collagen modulates Streptococcus mutans bacterial extracellular vesicle production and cargo

C Leiva-Sabadini, P Berríos, P Saavedra… - bioRxiv, 2024 - biorxiv.org
Streptococcus mutans is the major microbial etiological agent of dental caries and can
adhere to surfaces such as type-I collagen, present in dentin and periodontal tissues …

SloR-SRE binding to the S. mutans mntH promoter is cooperative.

M Ziogas, IY Drummond, I Todorovic, KN Kraczkowsky… - bioRxiv, 2024 - biorxiv.org
Streptococcus mutans is a commensal member of the plaque microbiome. It is especially
prevalent when dietary sugars are available for S. mutans fermentation, generating acid …