Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

In the current study, for the first time, the synergistic activity of curcumin and silver/copper
nanoparticles (NPs) was studied against Staphylococcus aureus and Pseudomonas …

Cell-to-cell communication is a major process that allows bacteria to sense and coordinately
react to the fluctuating conditions of the surrounding environment. In several pathogens, this …

Type IV pili (T4P) are one of the most common forms of bacterial and archaeal surface
structures, involved in adherence, motility, competence for DNA uptake, and pathogenesis …

Since its initial discovery as an allosteric factor regulating cellulose biosynthesis in
Gluconacetobacter xylinus, the list of functional outputs regulated by c-di-GMP has grown …

Biofilms are adherent aggregates of bacterial cells that form on biotic and abiotic surfaces,
including human tissues. Biofilms resist antibiotic treatment and contribute to bacterial …

Cyclic nucleotides represent second messenger molecules in all kingdoms of life. In
bacteria, mass sequencing of genomes detected the highly abundant protein domains …

The opportunistic human pathogen Pseudomonas aeruginosa effectively colonizes host
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …

In the present review, we describe and compare the molecular mechanisms that are
involved in the regulation of biofilm formation by P seudomonas putida, P seudomonas …