[HTML][HTML] Imaging drug delivery to the lungs: Methods and applications in oncology

F Man, J Tang, M Swedrowska, B Forbes… - Advanced Drug Delivery …, 2023 - Elsevier
Direct delivery to the lung via inhalation is arguably one of the most logical approaches to
treat lung cancer using drugs. However, despite significant efforts and investment in this …

[HTML][HTML] Molecular imaging in tracking tumor-specific cytotoxic T lymphocytes (CTLs)

Z Liu, Z Li - Theranostics, 2014 - ncbi.nlm.nih.gov
Despite the remarkable progress of adoptive T cell therapy in cancer treatment, there
remains an urgent need for the noninvasive tracking of the transfused T cells in patients to …

Evaluation of the therapeutic and diagnostic effects of PEGylated liposome–embedded 188Re on human non–small cell lung cancer using an orthotopic small-animal …

LT Lin, CH Chang, HL Yu, RS Liu… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Non–small cell lung cancer (NSCLC) is a highly morbid and mortal cancer type that is
difficult to eradicate using conventional chemotherapy and radiotherapy. Little is known …

PET imaging of oncolytic VSV expressing the mutant HSV-1 thymidine kinase transgene in a preclinical HCC rat model

KA Muñoz-Álvarez, J Altomonte, I Laitinen, S Ziegler… - Molecular Therapy, 2015 - cell.com
Hepatocellular carcinoma (HCC) is the most predominant form of liver cancer and the third
leading cause of cancer-related death worldwide. Due to the relative ineffectiveness of …

Therapeutic Nucleic Acids Against Herpes Simplex Viruses (A Review)

AS Levina, MN Repkova, VF Zarytova - Russian Journal of Bioorganic …, 2023 - Springer
The Herpes simplex virus (HSV) causes a wide range of diseases ranging from relatively
mild primary skin lesions to severe and often fatal episodes of encephalitis. Currently, the …

Radiochemical synthesis of 2′‐[18F]‐labelled and 3′‐[18F]‐labelled nucleosides for positron emission tomography imaging

JP Meyer, KC Probst… - Journal of Labelled …, 2014 - Wiley Online Library
This review article considers 2′‐labelled and 3′‐labelled nucleosides, which are of great
importance as positron emission tomography (PET) probes in clinical diagnostics and PET …

Radiolabeled nucleosides for predicting and monitoring the cancer therapeutic efficacy of chemodrugs

CY Wu, HE Wang, MH Lin, LS Chu… - Current medicinal …, 2012 - ingentaconnect.com
Uncontrolled cell proliferation is an important hallmark of cancer. Cancer treatment with
cytostatic chemodrugs usually results in insignificant changes in tumor size, and thus limits …

Therapeutic Nucleic Acids against Herpes Simplex Viruses

AS Levina, MN Repkova… - Bioorganičeskaâ himiâ, 2023 - journals.rcsi.science
The Herpes simplex virus (HSV) causes a wide range of diseases, ranging from relatively
mild primary skin lesions to severe and often fatal episodes of encephalitis. Currently, the …

Radioimaging of Activated T Cells in Preclinical and Clinical Cancer Investigations

Á Roxin, F Bénard - Nuclear Medicine and Immunology, 2022 - Springer
This chapter is meant to present readers with detailed accounts of studies that have used
either directly labeled or indirectly labeled activated T cells to gain insights into the complex …

Monitoring tumor response with [18F] FMAU in a sarcoma-bearing mouse model after liposomal vinorelbine treatment

PC Chan, CY Wu, WT Chang, CY Lin, YL Tseng… - Nuclear Medicine and …, 2013 - Elsevier
Objective Previous studies have shown that the accumulation level of FMAU in tumor is
proportional to its proliferation rate. This study demonstrated that 2′-deoxy-2′-[18 F] fluoro …