Astrocyte endfeet enwrap the entire vascular tree within the central nervous system, where
they perform important functions in regulating the blood-brain barrier (BBB), cerebral blood …

Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

Objective The glymphatic system cleans amyloid and tau proteins from the brain in animal
studies of Alzheimer disease (AD). However, there is no direct evidence showing this in …

The mechanism of cognitive impairment in patients with cerebral small vessel disease
(CSVD) remains unknown. The glymphatic system dysfunction, which has been …

Objective This study aims to investigate the associations of glymphatic system with the
presence, severity and neuroimaging phenotypes of cerebral small vessel disease (CSVD) …

Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …

Objectives To investigate glymphatic function in Alzheimer's disease (AD) using the diffusion
tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the …

Recently, an astrocytic aquaporin 4-dependent drainage system, that is, the glymphatic
system, has been identified in the live murine and human brain. Growing evidence suggests …

The glymphatic system is a unique pathway that utilises end-feet Aquaporin 4 (AQP4)
channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid …

Objective A growing body of research examining the effect of exercise on cognitive function
in people with multiple sclerosis (MS), while findings of available studies were conflicting …