The oral and maxillofacial region comprises a variety of organs made up of multiple soft and
hard tissue, which are anatomically vulnerable to the pathogenic factors of trauma …

This Review explores the evolution, improvements, and recent applications of Light Sheet
Fluorescence Microscopy (LSFM) in biological research using a high numerical aperture …

Exact three-dimensional (3D) structural information of developing organoids is key for
optimising organoid generation and for studying experimental outcomes in organoid …

Single-molecule localization microscopy has revealed cellular architectures and molecular
dynamics beyond the diffraction limit of light. However, imaging thick samples presents …

Live cell imaging is essential for obtaining spatial and temporal insights into dynamic
molecular events within heterogeneous individual cells, in situ intracellular networks, and in …

As light sheet fluorescence microscopy (LSFM) becomes widely available, reconstruction of
time-lapse imaging will further our understanding of complex biological processes at cellular …

Whole-mount 3D imaging at the cellular scale is a powerful tool for exploring the complex
processes of organoid morphogenesis, as it allows examining tissue architecture, cell types …

The spontaneous emergence of tissue patterns is often attributed to biochemical reaction-
diffusion systems. In Hydra tissue regeneration, the formation of a Wnt signaling center …

Heart development involves the specification of cardiac progenitors at distinct stages and
locations. Using live-imaging of mouse embryos between gastrulation and heart tube …

The evaluation of DNA damage response, particularly DNA damage foci formation, is crucial
for understanding tumor biology and assessing the impacts of various drugs. We have …