[HTML][HTML] A comprehensive insight into current control of COVID-19: Immunogenicity, vaccination, and treatment.

Y Mohamed, YA El-Maradny, AK Saleh… - Biomedicine & …, 2022 - Elsevier
The healthy immune system eliminates pathogens and maintains tissue homeostasis
through extraordinarily complex networks with feedback systems while avoiding potentially …

Non-mammalian eukaryotic expression systems yeast and fungi in the production of biologics

M Garvey - Journal of Fungi, 2022 - mdpi.com
Biologics have become an important area of medical research generating therapeutics
essential for the treatment of many disease states. Biologics are defined as biologically …

Novel Exopolysaccharide from Marine Bacillus subtilis with Broad Potential Biological Activities: Insights into Antioxidant, Anti-Inflammatory, Cytotoxicity, and Anti …

BA Abdel-Wahab, H F. Abd El-Kareem, A Alzamami… - Metabolites, 2022 - mdpi.com
In the presented study, Bacillus subtilis strain AG4 isolated from marine was identified based
on morphological, physiological, phylogenetic characteristics and an examination of 16S …

Novel 1, 3-thiazole analogues with potent activity against breast cancer: A design, synthesis, in vitro, and in silico study

MG Salem, DMA El-Maaty, YIM El-Deen, BH Elesawy… - Molecules, 2022 - mdpi.com
Breast cancer is the most common cancer in women, responsible for over half a million
deaths in 2020. Almost 75% of FDA-approved drugs are mainly nitrogen-and sulfur …

Development of Novel 1,3-Disubstituted-2-Thiohydantoin Analogues with Potent Anti-Inflammatory Activity; In Vitro and In Silico Assessments

SM Khirallah, HMM Ramadan, A Shawky, SH Qahl… - Molecules, 2022 - mdpi.com
Inflammation is the main cause of several autoimmune diseases, including type I diabetes,
rheumatoid arthritis, bullous pemphigoid, paraneoplastic pemphigoid, and multiple …

Hepatoprotective role of carvedilol against ischemic hepatitis associated with acute heart failure via targeting MiRNA-17 and mitochondrial dynamics-related proteins …

DI Mohamed, SF Ezzat, WM Elayat, OA El-Kharashi… - Pharmaceuticals, 2022 - mdpi.com
Acute heart failure (AHF) is one of the most common diseases in old age that can lead to
mortality. Systemic hypoperfusion is associated with hepatic ischemia–reperfusion injury …

Acetylsalicylic acid suppresses alcoholism-induced cognitive impairment associated with atorvastatin intake by targeting cerebral miRNA155 and NLRP3: in vivo, and …

DI Mohamed, D Alaa El-Din Aly El-Waseef, ES Nabih… - Pharmaceutics, 2022 - mdpi.com
Alcoholism is one of the most common diseases that can lead to the development of several
chronic diseases including steatosis, and cognitive dysfunction. Statins are lipid-lowering …

Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for …

EM Radwan, E Abo-Elabass, AE Abd El-Baky… - Frontiers in …, 2023 - frontiersin.org
Being the sixth most diagnosed cancer and the fourth leading cause of cancer-related
deaths worldwide, liver cancer is considered as a serious disease with a high prevalence …

In Situ Biosynthesis of Reduced Alpha Hematite (α-Fe2O3) Nanoparticles by Stevia Rebaudiana L. Leaf Extract: Insights into Antioxidant, Antimicrobial, and …

SZ Alshawwa, EJ Mohammed, N Hashim, M Sharaf… - Antibiotics, 2022 - mdpi.com
In the present study, we utilized Stevia rebaudiana L.(SRLe) extract to in situ biosynthesize
nanoscale alpha hematite (α-Fe2O3) nanoparticles (NPs) with potent antioxidant …

Insights into Asparaginase from Endophytic Fungus Lasiodiplodia theobromae: Purification, Characterization and Antileukemic Activity

HA Moubasher, BA Balbool, YA Helmy… - International journal of …, 2022 - mdpi.com
Endobiotic fungi are considered as a reservoir of numerous active metabolites.
Asparaginase is used as an antileukemic drug specially to treat acute lymphoblastic …