Peptide self-assembly is the process by which peptide molecules aggregate into low
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …

Tauopathies are a class of neurodegenerative diseases correlated with the presence of
pathological Tau fibrils as a diagnostic marker. The microtubule-binding repeat region of …

Tau dysfunction has a close association with many neurodegenerative diseases, which are
collectively referred to as tauopathies. Neurofibrillary tangles (NFTs) formed by misfolding …

Hypochlorous acid (HOCl) released from activated leukocytes not only plays a significant
role in the human immune system but is also implicated in numerous diseases including …

The aggregation and structural conversion of normal prion peptide (PrPC) into the
pathogenic scrapie form (PrPSc), which can act as a seed to enhance prion amyloid fiber …

Monitoring early-stage β-amyloid (Aβ) dimerization is a formidable challenge for
understanding neurological diseases. We compared β-sheet formation and histidine site …

Controlling protein misfolding and accumulation in neurodegeneration is a challenge in
chemical neuroscience. The application of appropriate electric fields (EFs) can be a …

Tau proteins are recently gaining a lot of interest due to their active role in causing a range
of tauopathies. Molecular mechanisms underlying the tau interaction with the neuronal …

C9orf72 is a major genetic factor in Amyotrophic Lateral Sclerosis (ALS), a
neurodegenerative disorder affecting brain and spinal cord neurons, and comprehending its …

Hundreds of millions of people around the world have been affected by Type 2 diabetes
(T2D) which is a metabolic disorder. Clinical research has revealed T2D as a possible risk …