Nanotechnologies are emerging as highly promising technologies in many sectors in the
society. However, the increasing use of engineered nanomaterials also raises concerns …

Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

The asymmetric phospholipid distribution in plasma membranes is normally maintained by
energy-dependent lipid transporters that translocate different phospholipids from one …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder. A number of
hypotheses have been proposed to explain AD pathogenesis. One such hypothesis …

Malignant melanoma is one the most aggressive types of cancer and its incidence has
gradually increased in the last years, accounting for about 75% of skin cancer deaths. This …

The process of apoptosis includes critically important changes on the cell surface that lead
to its recognition and removal. The recognition also generates a number of other local tissue …

Lipid peroxidation occurs in the context of many physiological processes but is greatly
increased in various pathological situations. A consequence of phospholipid peroxidation is …

The oxidation of lipids has been shown to impact virtually all cellular processes. The
paradigm has been that this involvement is due to interference with the functions of …

The evidence that oxidized phospholipids play a role in signaling, apoptotic events and in
age-related diseases is responsible for the increasing interest for the study of this subject …

The “Fluid Mosaic Model”, described by Singer and Nicolson, explain both how a cell
membrane preserves a critical barrier function while it concomitantly facilitates rapid lateral …