Oxidative stress in liver pathophysiology and disease
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …
not only arise during metabolic functions but also during the biotransformation of …
The mechanisms of HBV-induced hepatocellular carcinoma
Y Jiang, Q Han, H Zhao, J Zhang - Journal of hepatocellular …, 2021 - Taylor & Francis
Hepatocellular carcinoma (HCC) is a common malignancy, and the hepatitis B virus (HBV) is
its major pathogenic factor. Over the past decades, it has been confirmed that HBV infection …
its major pathogenic factor. Over the past decades, it has been confirmed that HBV infection …
Hepatitis virus and hepatocellular carcinoma: recent advances
C Shen, X Jiang, M Li, Y Luo - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …
Hepatitis B virus-associated hepatocellular carcinoma
Hepatitis B virus (HBV) is DNA-based virus, member of the Hepadnaviridae family, which
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …
TXNIP: A Double‐Edged Sword in Disease and Therapeutic Outlook
M Pan, F Zhang, K Qu, C Liu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Thioredoxin‐interacting protein (TXNIP) was originally named vitamin D3 upregulated
protein‐1 (VDUP1) because of its ability to bind to thioredoxin (TRX) and inhibit TRX …
protein‐1 (VDUP1) because of its ability to bind to thioredoxin (TRX) and inhibit TRX …
原发性肝癌流行现状, 主要发病机制及防控策略
鲜林峰， 方乐天， 刘文斌， 赵沛， 陈一凡， 曹广文 - 中国癌症防治杂志, 2022 - zgazfz.com
原发性肝癌是世界范围内主要的癌症死亡原因之一, 早期筛查高危人群并进行有效的三级预防是
当前降低肝癌死亡率的主要策略. 本文总结了目前原发性肝癌的流行特征和主要致病因素; …
当前降低肝癌死亡率的主要策略. 本文总结了目前原发性肝癌的流行特征和主要致病因素; …
The role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control
Thioredoxin-interacting protein (TXNIP) is commonly considered a master regulator of
cellular oxidation, regulating the expression and function of Thioredoxin (Trx). Recent work …
cellular oxidation, regulating the expression and function of Thioredoxin (Trx). Recent work …
Hepatitis B viral protein HBx and the molecular mechanisms modulating the hallmarks of hepatocellular carcinoma: a comprehensive review
With 296 million cases estimated worldwide, chronic hepatitis B virus (HBV) infection is the
most common risk factor for hepatocellular carcinoma (HCC). HBV-encoded oncogene X …
most common risk factor for hepatocellular carcinoma (HCC). HBV-encoded oncogene X …
Relevance of HBx for hepatitis B virus-associated pathogenesis
A Schollmeier, M Glitscher, E Hildt - International Journal of Molecular …, 2023 - mdpi.com
The hepatitis B virus (HBV) counts as a major global health problem, as it presents a
significant causative factor for liver-related morbidity and mortality. The development of …
significant causative factor for liver-related morbidity and mortality. The development of …
Aerobic glycolysis enhances HBx-initiated hepatocellular carcinogenesis via NF-κBp65/HK2 signalling
L Chen, X Lin, Y Lei, X Xu, Q Zhou, Y Chen… - Journal of Experimental …, 2022 - Springer
Background Aerobic glycolysis has been recognized as one of the growth-promoting
metabolic alterations of cancer cells. Emerging evidence indicates that nuclear factor κB (NF …
metabolic alterations of cancer cells. Emerging evidence indicates that nuclear factor κB (NF …