Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …

Chemokines have fundamental roles in regulating immune and inflammatory responses,
primarily through their control of leukocyte migration and localization. The biological …

There are no licensed vaccines against Plasmodium vivax. We conducted two phase 1/2a
clinical trials to assess two vaccines targeting P. vivax Duffy-binding protein region II …

More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of
severe malaria is still not well understood. The majority of malaria cases are caused by …

Research into the aetiological agent of the most widespread form of severe malaria,
Plasmodium falciparum, has benefitted enormously from the ability to culture and genetically …

Plasmodium vivax is the leading cause of human malaria in Asia and Latin America but is
absent from most of central Africa due to the near fixation of a mutation that inhibits the …

Malaria in sub-Saharan Africa has historically been almost exclusively attributed to
Plasmodium falciparum (Pf). Current diagnostic and surveillance systems in much of sub …

Malaria and leishmaniasis are endemic parasitic diseases in tropical and subtropical
countries. Although the overlap of these diseases in the same host is frequently described …

Understanding the life cycle of Plasmodium vivax is fundamental for developing strategies
aimed at controlling and eliminating this parasitic species. Although advances in omic …

The human DARC (Duffy antigen receptor for chemokines) gene encodes a membrane-
bound chemokine receptor crucial for the infection of red blood cells by Plasmodium vivax, a …