Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer

S Mirzaei, MH Gholami, A Zabolian, H Saleki… - Pharmacological …, 2021 - Elsevier
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Molecular and cellular mechanisms of propolis and its polyphenolic compounds against cancer

N Oršolić, M Jazvinšćak Jembrek - International journal of molecular …, 2022 - mdpi.com
In recent years, interest in natural products such as alternative sources of pharmaceuticals
for numerous chronic diseases, including tumors, has been renewed. Propolis, a natural …

Efficacy of caffeic acid on diabetes and its complications in the mouse

N Oršolić, D Sirovina, D Odeh, G Gajski, V Balta, L Šver… - Molecules, 2021 - mdpi.com
Diabetic dyslipidemia and hyperglycemia contribute to excessive reactive oxygen species
(ROS) production, leading to deleterious complications, such as nephropathy …

[HTML][HTML] Redox control of cancer cell destruction

C Hegedűs, K Kovács, Z Polgár, Z Regdon, É Szabó… - Redox biology, 2018 - Elsevier
Redox regulation has been proposed to control various aspects of carcinogenesis, cancer
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …

[HTML][HTML] Reactive oxygen species in immune cells: A new antitumor target

L Wang, Z Kuang, D Zhang, Y Gao, M Ying… - Biomedicine & …, 2021 - Elsevier
Immune cells have the potential to control the growth of tumor. However, this effect could be
offset by immunosuppression associated with an increased production of reactive oxygen …

Effect of propolis on diet-induced hyperlipidemia and atherogenic indices in mice

N Oršolić, I Landeka Jurčević, D Đikić, D Rogić… - Antioxidants, 2019 - mdpi.com
Obesity, a major health problem worldwide, is associated with increased cardiovascular risk
factors, such as dyslipidemia, glucose intolerance, and hypertension. We investigated the …

Regulation of PD-L1 expression on cancer cells with ROS-modulating drugs

C Bailly - Life Sciences, 2020 - Elsevier
Monoclonal antibodies targeting the programmed-death 1 (PD-1) immune checkpoint or its
ligand PD-L1 have significantly improved the treatment of cancers but more efficient drugs …

Therapeutic implications and clinical manifestations of thymoquinone

M Alam, GM Hasan, MM Ansari, R Sharma, DK Yadav… - Phytochemistry, 2022 - Elsevier
Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …

Immunity as cornerstone of non-alcoholic fatty liver disease: the contribution of oxidative stress in the disease progression

M Dallio, M Sangineto, M Romeo, R Villani… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of
metabolic syndrome and has become the major cause of chronic liver disease, especially in …