[HTML][HTML] Epidemiology of cholera

J Deen, MA Mengel, JD Clemens - Vaccine, 2020 - Elsevier
Cholera is an ancient disease that remains a public health problem in many impoverished
locations around the world. Seven pandemics of cholera have been recorded since the first …

Diagnosis, management, and future control of cholera

F Chowdhury, AG Ross, MT Islam… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Cholera, caused by Vibrio cholerae, persists in developing countries due to inadequate
access to safe water, sanitation, and hygiene. There are approximately 4 million cases and …

[HTML][HTML] Cholera toxin B: one subunit with many pharmaceutical applications

KJ Baldauf, JM Royal, KT Hamorsky, N Matoba - Toxins, 2015 - mdpi.com
Cholera, a waterborne acute diarrheal disease caused by Vibrio cholerae, remains
prevalent in underdeveloped countries and is a serious health threat to those living in …

[HTML][HTML] Current and future cholera vaccines

H Shaikh, J Lynch, J Kim, JL Excler - Vaccine, 2020 - Elsevier
Cholera remains a major global public health problem that is primarily linked to insufficient
access to safe water and proper sanitation. Oral Cholera Vaccine (OCV) has been …

[HTML][HTML] Emerging concepts in cholera vaccine design

B Sit, B Fakoya, MK Waldor - Annual Review of Microbiology, 2022 - annualreviews.org
Cholera is a severe diarrheal disease caused by the bacterium Vibrio cholerae and
constitutes a significant public health threat in many areas of the world. V. cholerae infection …

Comparison of immune responses to the O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi adult patients with cholera

RA Johnson, T Uddin, A Aktar, M Mohasin… - Clinical and Vaccine …, 2012 - Am Soc Microbiol
Immunity against Vibrio cholerae O1 is serogroup specific, and serogrouping is defined by
the O-specific polysaccharide (OSP) part of lipopolysaccharide (LPS). Despite this, human …

[HTML][HTML] A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy …

MA Sayeed, MK Bufano, P Xu, G Eckhoff… - PLoS neglected …, 2015 - journals.plos.org
Background Vibrio cholerae is the cause of cholera, a severe watery diarrhea. Protection
against cholera is serogroup specific. Serogroup specificity is defined by the O-specific …

[HTML][HTML] Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among …

A Aktar, MA Rahman, S Afrin, A Akter… - PLoS neglected …, 2018 - journals.plos.org
Background The mediators of protection against cholera, a severe dehydrating illness of
humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma …

[HTML][HTML] B-Cell Epitope Mapping of the Vibrio cholera Toxins A, B, and P and an ELISA Assay

SG De-Simone, P Napoleão-Pêgo… - International Journal of …, 2022 - mdpi.com
Oral immunization with the choleric toxin (CT) elicits a high level of protection against its
enterotoxin activities and can control cholera in endemic settings. However, the complete B …

[HTML][HTML] Protection afforded by previous Vibrio cholerae infection against subsequent disease and infection: A review

T Leung, L Matrajt - PLOS Neglected Tropical Diseases, 2021 - journals.plos.org
Background Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139
that is associated with a high global burden. Methods We analyzed the estimated duration of …