Overcoming skin barriers through advanced transdermal drug delivery approaches

V Phatale, KK Vaiphei, S Jha, D Patil, M Agrawal… - Journal of controlled …, 2022 - Elsevier
Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

Functional nano-systems for transdermal drug delivery and skin therapy

L Liu, W Zhao, Q Ma, Y Gao, W Wang, X Zhang… - Nanoscale …, 2023 - pubs.rsc.org
Transdermal drug delivery is one of the least intrusive and patient-friendly ways for
therapeutic agent administration. Recently, functional nano-systems have been …

Recent advances in oral and transdermal protein delivery systems

Y Yang, R Zhou, Y Wang, Y Zhang, J Yu… - Angewandte …, 2023 - Wiley Online Library
Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

Nano-formulations for transdermal drug delivery: A review

X Zhou, Y Hao, L Yuan, S Pradhan, K Shrestha… - Chinese Chemical …, 2018 - Elsevier
Transdermal drug delivery refers to a means of delivering drugs through the surface of the
skin for local or systemic treatment. The drug functions after absorption through the skin into …

Current advances in lipid nanosystems intended for topical and transdermal drug delivery applications

N Akombaetwa, AB Ilangala, L Thom, PB Memvanga… - Pharmaceutics, 2023 - mdpi.com
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug
delivery due to its ease of administration, ease of handling, high flexibility, controlled …

Recent advances in lipid-based vesicles and particulate carriers for topical and transdermal application

S Jain, N Patel, MK Shah, P Khatri, N Vora - Journal of pharmaceutical …, 2017 - Elsevier
In the recent decade, skin delivery (topical and transdermal) has gained an unprecedented
popularity, especially due to increased incidences of chronic skin diseases, demand for …

Pharmaceutical nanocrystals: A promising approach for improved topical drug delivery

PK Parmar, J Wadhawan, AK Bansal - Drug Discovery Today, 2021 - Elsevier
The barrier function of skin and the non-optimal physicochemical properties of drugs present
challenges to the skin penetration of many drugs, thus motivating the development of novel …

Where microneedle meets biomarkers: futuristic application for diagnosing and monitoring localized external organ diseases

A Himawan, LK Vora, AD Permana… - Advanced …, 2023 - Wiley Online Library
Extracellular tissue fluids are interesting biomatrices that have recently attracted scientists'
interest. Many significant biomarkers for localized external organ diseases have been …

Transdermal drug delivery and patches—An overview

D Bird, NM Ravindra - Medical Devices & Sensors, 2020 - Wiley Online Library
Transdermal drug delivery is a multibillion‐dollar industry, with an average of one
transdermal being approved by the Federal Drug Administration every 2.2 years. The first …