C yanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation

FM Buratti, M Manganelli, S Vichi, M Stefanelli… - Archives of …, 2017 - Springer
Cyanobacteria were present on the earth 3.5 billion years ago; since then they have
colonized almost all terrestrial and aquatic ecosystems. They produce a high number of …

Effects of cyanobacterial toxins on the human gastrointestinal tract and the mucosal innate immune system

B Kubickova, P Babica, K Hilscherová… - Environmental Sciences …, 2019 - Springer
Background Cyanobacterial blooms occur with increasing frequency in freshwater
ecosystems, posing a hazard to human and environmental health. Exposure of human to …

Update on the adverse effects of microcystins on the liver

L Shi, X Du, H Liu, X Chen, Y Ma, R Wang, Z Tian… - Environmental …, 2021 - Elsevier
Microcystins (MCs) are the most common cyanobacteria toxins in eutrophic water, which
have strong hepatotoxicity. In the past decade, epidemiological and toxicological studies on …

Oxygen-generating cyanobacteria powered by upconversion-nanoparticles-converted near-infrared light for ischemic stroke treatment

J Wang, Q Su, Q Lv, B Cai, X Xiaohalati, G Wang… - Nano Letters, 2021 - ACS Publications
Stroke is one of most common causes of death and disability. Most of neuroprotective agents
fail to rescue neurons from cerebral ischemic insults, mainly because of targeting …

Microcystin-RR: Occurrence, content in water and food and toxicological studies. A review

L Díez-Quijada, M Puerto, D Gutiérrez-Praena… - Environmental …, 2019 - Elsevier
Microcystins (MCs) are hepatotoxins, produced by various species of cyanobacteria, whose
occurrence is increasing worldwide owing to climate change and anthropogenic activities …

Natural cyclopeptides as anticancer agents in the last 20 years

JN Zhang, YX Xia, HJ Zhang - International Journal of Molecular Sciences, 2021 - mdpi.com
Cyclopeptides or cyclic peptides are polypeptides formed by ring closing of terminal amino
acids. A large number of natural cyclopeptides have been reported to be highly effective …

Microcystin-LR-induced changes of hepatopancreatic transcriptome, intestinal microbiota, and histopathology of freshwater crayfish (Procambarus clarkii)

Y Zhang, Z Li, S Kholodkevich, A Sharov, Y Feng… - Science of the Total …, 2020 - Elsevier
As a hepatotoxin, microcystin-LR (MC-LR) poses a great threat to aquatic organisms. In this
research, the hepatopancreatic transcriptome, intestinal microbiota, and histopathology of …

Immunotoxic effects induced by microcystins and cylindrospermopsin: A review

L Diez-Quijada, MM Benítez-González, M Puerto, A Jos… - Toxins, 2021 - mdpi.com
Cyanotoxin occurrence is gaining importance due to anthropogenic activities, climate
change and eutrophication. Among them, Microcystins (MCs) and Cylindrospermopsin …

Microcystin-LR triggers different endoplasmic reticulum stress pathways in the liver, ovary, and offspring of zebrafish (Danio rerio)

C Zhan, W Liu, F Zhang, X Zhang - Journal of hazardous materials, 2020 - Elsevier
The existence of microcystins (MCs), the secondary metabolite of cyanobacteria, has
become a growing public health concern. Previous researches have proved that MCs can …

Hepatotoxicity and immunotoxicity of MC-LR on silver carp

X Li, J Li, F Meng, L Yao - Ecotoxicology and Environmental Safety, 2019 - Elsevier
Microcystins produced by some cyanobacteria can cause damages to the liver and kidneys
of aquatic animals. In the natural water with cyanobacterial blooms, silver carp may suffer …