[图书][B] An introduction to outlier analysis

CC Aggarwal, CC Aggarwal - 2017 - Springer
Outliers are also referred to as abnormalities, discordants, deviants, or anomalies in the data
mining and statistics literature. In most applications, the data is created by one or more …

The pathogenesis of the antiphospholipid syndrome

B Giannakopoulos, SA Krilis - New England Journal of Medicine, 2013 - Mass Medical Soc
The antiphospholipid syndrome is a prothrombotic disorder associated with autoantibodies.
It is associated with obstetrical complications (mainly spontaneous abortion) as well as …

Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS

S Chaturvedi, EM Braunstein, X Yuan… - Blood, The Journal …, 2020 - ashpublications.org
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I …

Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the …

S Yalavarthi, TJ Gould, AN Rao, LF Mazza… - Arthritis & …, 2015 - Wiley Online Library
Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …

Annexins: from structure to function

V Gerke, SE Moss - Physiological reviews, 2002 - journals.physiology.org
Annexins are Ca2+ and phospholipid binding proteins forming an evolutionary conserved
multigene family with members of the family being expressed throughout animal and plant …

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

RA Ali, AA Gandhi, H Meng, S Yalavarthi… - Nature …, 2019 - nature.com
Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which
antiphospholipid antibodies (aPL Abs) effect thrombotic events in patients with …

Annexin A2 heterotetramer: structure and function

A Bharadwaj, M Bydoun, R Holloway… - International journal of …, 2013 - mdpi.com
Annexin A2 is a pleiotropic calcium-and anionic phospholipid-binding protein that exists as
a monomer and as a heterotetrameric complex with the plasminogen receptor protein …

[HTML][HTML] Unconventional secretion of annexins and galectins

SJ Popa, SE Stewart, K Moreau - Seminars in cell & developmental biology, 2018 - Elsevier
Eukaryotic cells have a highly evolved system of protein secretion, and dysfunction in this
pathway is associated with many diseases including cancer, infection, metabolic disease …

At the Bedside: Neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases

A Barnado, LJ Crofford, JC Oates - Journal of Leucocyte Biology, 2016 - academic.oup.com
Neutrophil extracellular traps are associated with a unique form of cell death distinct from
apoptosis or necrosis, whereby invading microbes are trapped and killed. Neutrophil …

[HTML][HTML] Coagulation disorders and thrombosis in COVID-19 patients and a possible mechanism involving endothelial cells: a review

A Chen, C Wang, W Zhu, W Chen - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is still an ongoing pandemic worldwide.
COVID-19 is an age-related disease with a higher risk of organ dysfunction and mortality in …