8-Oxoguanine: from oxidative damage to epigenetic and epitranscriptional modification

JY Hahm, J Park, ES Jang, SW Chi - Experimental & molecular …, 2022 - nature.com
In pathophysiology, reactive oxygen species control diverse cellular phenotypes by
oxidizing biomolecules. Among these, the guanine base in nucleic acids is the most …

The carcinogenic effects of formaldehyde occupational exposure: a systematic review

C Protano, G Buomprisco, V Cammalleri, RN Pocino… - Cancers, 2021 - mdpi.com
Simple Summary Formaldehyde is a chemical compound present in many working activities
and indoor workplaces. Occupational exposure occurs primarily by inhaling airborne …

A review of disrupted biological response associated with volatile organic compound exposure: Insight into identification of biomarkers

Q Shen, Y Liu, G Li, T An - Science of the Total Environment, 2024 - Elsevier
Volatile organic compounds (VOCs) are widespread harmful atmospheric pollutants, which
have long been concerned and elucidated to be one of the risks of acute and chronic …

[HTML][HTML] Biomarkers of nucleic acid oxidation–A summary state-of-the-art

MR Chao, MD Evans, CW Hu, Y Ji, P Møller, P Rossner… - Redox Biology, 2021 - Elsevier
Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …

Oxidative modifications of RNA and its potential roles in biosystem

M Tanaka, PB Chock - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Elevated level of oxidized RNA was detected in vulnerable neurons in Alzheimer patients.
Subsequently, several diseases and pathological conditions were reported to be associated …

Mapping the future of oxidative RNA damage in neurodegeneration: Rethinking the status quo with new tools

HB Wheeler, AA Madrigal, IA Chaim - … of the National Academy of Sciences, 2024 - pnas.org
Over two decades ago, increased levels of RNA oxidation were reported in postmortem
patients with ALS, Alzheimer's, Parkinson's, and other neurodegenerative diseases …

Reactive oxygen species and their consequences on the structure and function of mammalian spermatozoa

JR Drevet, J Hallak, MH Nasr-Esfahani… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Among the 200 or so cell types that comprise mammals, spermatozoa have an
ambiguous relationship with the reactive oxygen species (ROS) inherent in the consumption …

Protein denaturation inspired microchannel-based electrochemiluminescence sensor for formaldehyde detection

Y Huang, H Cai, F Luo, L Chen, C Lin, J Wang… - Biosensors and …, 2025 - Elsevier
Establishing an effective system to measure formaldehyde (HCHO) content in food is of
great significance due to food safety concern. Inspired by the mechanism of HCHO-induced …

Coping with RNA damage with a focus on APE1, a BER enzyme at the crossroad between DNA damage repair and RNA processing/decay

MC Malfatti, G Antoniali, M Codrich, G Tell - DNA repair, 2021 - Elsevier
Interest in RNA damage as a novel threat associated with several human pathologies is
rapidly increasing. Knowledge on damaged RNA recognition, repair, processing and decay …

Comparative transcriptome and metabolome analyses reveal the methanol dissimilation pathway of Pichia pastoris

Y Yu, J Yang, F Zhao, Y Lin, S Han - Bmc Genomics, 2022 - Springer
Abstract Background Pichia pastoris (Komagataella phaffii) is a model organism widely used
for the recombinant expression of eukaryotic proteins, and it can metabolize methanol as its …