Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …

Glaucoma, the world's leading cause of irreversible blindness, is a complex disease, with
differential presentation as well as ethnic and geographic disparities. The multifactorial …

Background: Retinal ganglion cell (RGC) degeneration is a major feature of glaucoma
pathology. Neuroprotective approaches that delay or halt the progression of RGC loss are …

Over the last decade, genetic studies, including genome-wide association studies (GWAS),
have accelerated the discovery of genes and genomic regions contributing to primary open …

Caveolae, specialized plasma membrane invaginations present in most cell types, play
important roles in multiple cellular processes including cell signaling, lipid uptake and …

Caveolae are specialized, invaginated plasma membrane domains that are defined
morphologically and by the expression of signature proteins called, caveolins. Caveolae …

Background Raising public awareness and knowledge about glaucoma is a key for early
case identification and prevention of blindness. However, awareness and knowledge about …

Primary open angle glaucoma (POAG) is a complex disease with a major genetic
contribution. Its prevalence varies greatly among ethnic groups, and is up to five times more …

Glaucoma is a group of progressive optic neuropathies that have in common characteristic
optic nerve head changes, loss of retinal ganglion cells and visual field defects. Among the …

Primary open-angle glaucoma (POAG) is a clinically important and genetically
heterogeneous cause of progressive vision loss as a result of retinal ganglion cell death …