Endometrial cancer is the most common gynaecological cancer in high income countries
and its incidence is rising globally. Although an ageing population and fewer benign …

Following the discovery of the four molecular subtypes of endometrial cancer (EC) by The
Cancer Genome Atlas (TCGA) in 2013, subsequent studies used surrogate markers to …

Although the incidence of endometrial carcinoma (EC) is similar in Black and White women,
racial disparities are stark, with the highest mortality rates observed among Black patients …

Molecular classification provides an objective, reproducible framework for categorization of
endometrial cancers (ECs), informing prognosis and selection of therapy. Currently, the …

Endometrial carcinomas (ECs) classified by The Cancer Genome Atlas (TCGA) as copy
number-low (also referred to as “no specific molecular profile”[NSMP]) have a prognosis …

Purpose: The clinical significance of the p53-abnormal (p53abn) molecular subtype in stage
I low-grade endometrioid endometrial carcinoma (EEC) is debated. We aimed to review …

Background We investigated the utility of a molecular classifier tool and genetic alterations
for predicting prognosis in Japanese patients with endometrial cancer. Methods A total of …

Purpose Using next generation sequencing (NGS), The Cancer Genome Atlas (TCGA)
found that endometrial carcinomas (ECs) fall under one of four molecular subtypes, and a …

Purpose: Microsatellite instability–high (MSI-H) endometrial carcinomas are underpinned by
distinct mechanisms of DNA mismatch repair deficiency (MMR-D). We sought to characterize …

Background The role of lymph node assessment/dissection (LND) in endometrial cancer
(EC) has been debated for decades, with significant practice variation between centers …