Adverse childhood experiences run deep: toxic early life stress, telomeres, and mitochondrial DNA copy number, the biological markers of cumulative stress

KK Ridout, M Khan, SJ Ridout - Bioessays, 2018 - Wiley Online Library
This manuscript reviews recent evidence supporting the utility of telomeres and
mitochondrial DNA copy number (mtDNAcn) in detecting the biological impacts of adverse …

Oxidative dysregulation in early life stress and posttraumatic stress disorder: a comprehensive review

E Karanikas, NP Daskalakis, A Agorastos - Brain Sciences, 2021 - mdpi.com
Traumatic stress may chronically affect master homeostatic systems at the crossroads of
peripheral and central susceptibility pathways and lead to the biological embedment of …

Acute neuroinflammation elicited by TLR-3 systemic activation combined with early life stress induces working memory impairments in male adolescent mice

TW Viola, KC Creutzberg, A Zaparte… - Behavioural brain …, 2019 - Elsevier
Abstract Toll-like Receptors (TLRs) are implicated with the pathogenesis of cognitive
impairment induced by inflammation. Early life stress is associated with altered trajectories …

Common environmental factors may underpin the comorbidity between generalized anxiety disorder and mood disorders via activated nitro-oxidative pathways

C Roomruangwong, DS Simeonova… - Current topics in …, 2018 - ingentaconnect.com
Generalized Anxiety Disorder (GAD) commonly co-occurs with mood disorders, especially
Major Depressive Disorder (MDD) and bipolar disorder (BD), which are accompanied by …

Associations between Phthalate Exposure and Gestational Age at Delivery in a Diverse Pregnancy Cohort

L Sienas, C Albright, Y Ni, A Szpiro, NR Bush, C Loftus… - Toxics, 2022 - mdpi.com
The association between prenatal phthalate exposure and late preterm birth (LPTB) is
unclear. We examined singleton pregnancies (2006–2011) from a racially and …