Diet‐induced rodent models of obesity‐related metabolic disorders—a guide to a translational perspective

I Preguiça, A Alves, S Nunes, R Fernandes… - Obesity …, 2020 - Wiley Online Library
Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

Hormonal and metabolite regulation of hepatic glucokinase

L Agius - Annual review of nutrition, 2016 - annualreviews.org
Liver glucose metabolism is dependent on glucokinase activity. Glucokinase expression is
transcriptionally regulated by hormones and metabolites of glucose, and glucokinase activity …

Activation of Nrf2 signaling by sitagliptin and quercetin combination against β‐amyloid induced Alzheimer's disease in rats

Y Li, Q Tian, Z Li, M Dang, Y Lin… - Drug development …, 2019 - Wiley Online Library
The objective of this study was to evaluate the neuroprotective effect of sitagliptin (Sita),
quercetin (QCR) and its combination in β‐amyloid (Aβ) induced Alzheimer's disease (AD) …

[HTML][HTML] The glucagon-like peptide-1 analogue exendin-4 reverses impaired intracellular Ca2+ signalling in steatotic hepatocytes

ES Ali, J Hua, CH Wilson, GA Tallis, FH Zhou… - … et Biophysica Acta (BBA …, 2016 - Elsevier
The release of Ca 2+ from the endoplasmic reticulum (ER) and subsequent replenishment of
ER Ca 2+ by Ca 2+ entry through store-operated Ca 2+ channels (SOCE) play critical roles …

Perfluorooctanoic acid exposure disturbs glucose metabolism in mouse liver

F Zheng, N Sheng, H Zhang, S Yan, J Zhang… - Toxicology and Applied …, 2017 - Elsevier
Environmental pollutants such as perfluorooctanoic acid (PFOA) can influence human
metabolism processes and are associated with certain metabolic diseases. To investigate …

Quantum dots as förster resonance energy transfer acceptors of lanthanides in time-resolved bioassays

SA Díaz, G Lasarte-Aragones, RG Lowery… - ACS Applied Nano …, 2018 - ACS Publications
We report a flexible and modular design for biosensors based on exploiting semiconductor
quantum dots (QDs) and their excellent Förster resonance energy transfer (FRET) acceptor …

Mechanism of preventive effects of exendin-4 and des-fluoro-sitagliptin in a murine model of fructose-induced prediabetes

MC Castro, HG Villagarcía, G Schinella… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Protective effects of exendin-4 (glucagon-like peptide-1-GLP-1-receptor agonist) and des-
fluoro-sitagliptin (dipeptidyl peptidase-4 inhibitor) on fructose-induced hepatic disturbances …

مروری بر روش‌های ایجاد سندرم متابولیک در موش‌های صحرایی: راهنمای کاربردی ایجاد مدل با تجویز رژیم پرکربوهیدرات

جدی, قاسمی - مجله ی غدد درون‌ریز و متابولیسم ایران، دو ماهنامه پژوهشی …, 2023‎ - ijem.sbmu.ac.ir
سندرم متابولیک به مجموعه‌ای از عوامل خطر مرتبط با بیماری‌های قلبی عروقی و دیابت نوع 2؛ شامل
پرفشاری خون، دیس‌لیپیدمی، افزایش گلوکز ناشتا و چاقی، که اغلب با هم اتفاق می‌افتند، گفته …

Preclinical impact of blueberry supplementation in healthy and prediabetic conditions-Focus on gut microbiota and hepatic mitochondria bioenergetics

SRRP Nunes - 2021 - search.proquest.com
Prediabetes, recognized as a state of high risk for the development of type 2 diabetes
mellitus (T2DM) and related complications, is certainly a privileged phase to implement …

[PDF][PDF] Perfluorooctanoic Acid Exposure Disturbs Glucose Metabolism in Mouse Liver

郑飞, 盛南, 张红霞, 严晟旻, 张建海, 王建设 - 2017 - ir.ioz.ac.cn
Environmental pollutants such as perfluorooctanoic acid (PFOA) can influence human
metabolism processes and are associated with certain metabolic diseases. To investigate …