Review of noninvasive methods to characterize granular mixing
H Nadeem, TJ Heindel - Powder Technology, 2018 - Elsevier
Granular mixing is a common process observed in a variety of industries such as
construction, chemical processing, food handling, and cosmetics and pharmaceutical …
construction, chemical processing, food handling, and cosmetics and pharmaceutical …
Model-based scale-up methodologies for pharmaceutical granulation
In the pharmaceutical industry, it is a major challenge to maintain consistent quality of drug
products when the batch scale of a process is changed from a laboratory scale to a pilot or …
products when the batch scale of a process is changed from a laboratory scale to a pilot or …
Flow of granular materials in a bladed mixer: Effect of particle properties and process parameters on impeller torque and power consumption
V Boonkanokwong, RP Frank, P Valliappan… - Advanced powder …, 2018 - Elsevier
The torque and power needed to drive an impeller are important quantities that can indicate
flow behavior and can be used to control processes, especially mixing and granulation in …
flow behavior and can be used to control processes, especially mixing and granulation in …
Collapse and runout of granular columns in pendular state
AC Santomaso, S Volpato, F Gabrieli - Physics of Fluids, 2018 - pubs.aip.org
It is well known that even small amounts of liquid can strongly modify the mechanical
behavior of granular packings in static and dynamic conditions. This experimental work …
behavior of granular packings in static and dynamic conditions. This experimental work …
Scale-up and flow behavior of cohesive granular material in a four-bladed mixer: effect of system and particle size
V Boonkanokwong, JG Khinast, BJ Glasser - Advanced Powder …, 2021 - Elsevier
Flow of cohesive granular materials with different moisture contents was examined in a four-
bladed mixer via the discrete element method (DEM). Firstly, the mixer diameter (D) was …
bladed mixer via the discrete element method (DEM). Firstly, the mixer diameter (D) was …
Lubricant sensitivity in function of paddle movement in the forced feeder of a high-speed tablet press
E Peeters, V Vanhoorne, C Vervaet… - Drug Development and …, 2016 - Taylor & Francis
Context: The negative impact of magnesium stearate (MgSt) on the hardness of tablets is a
well-known phenomenon, but the influence of paddle movement in the forced feeder on the …
well-known phenomenon, but the influence of paddle movement in the forced feeder on the …
Multivariate feed forward process control and optimization of an industrial, granulation based tablet manufacturing line using historical data
The purpose of this work was to understand the variability in disintegration time and
tableting yield of high drug load (> 60%) tablets prepared by batch-wise high shear wet …
tableting yield of high drug load (> 60%) tablets prepared by batch-wise high shear wet …
Drag in wet granular materials
We have studied experimentally the effect of the water content on the drag force applied by a
wet granular system on a probe moving through it at constant velocity. Similar to what has …
wet granular system on a probe moving through it at constant velocity. Similar to what has …
Shear rate dependency on flowing granular biomass material
The commercialization of bioenergy has been significantly limited by various material
handling issues due to the poor flowability of granular biomass materials. Addressing these …
handling issues due to the poor flowability of granular biomass materials. Addressing these …
Dimensionless criteria as a tool for creation of a model for predicting the size of granules in high-shear granulation
This work deals with the creation of a mathematical model which will predict with sufficient
accuracy the size of granules in the high-shear granulation process. The aim of the paper …
accuracy the size of granules in the high-shear granulation process. The aim of the paper …