Recent advancements in hydrogels as novel tissue engineering scaffolds for dental pulp regeneration

X Guo, J Li, Y Wu, L Xu - International Journal of Biological Macromolecules, 2024 - Elsevier
Although conventional root canal treatment offers an effective therapeutic solution, it
negatively affects the viability of the affected tooth. In recent years, pulp regeneration …

Hypoxia effects on oncolytic virotherapy in Cancer: Friend or Foe?

M Sadri, A Najafi, A Rahimi, N Behranvand… - International …, 2023 - Elsevier
Researchers have tried to find novel strategies for cancer treatment in the past decades.
Among the utilized methods, administering oncolytic viruses (OVs) alone or combined with …

[HTML][HTML] Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures

MG da Costa Sousa, GC de Almeida, DCM Mota… - Bioactive Materials, 2022 - Elsevier
Multifunctional scaffolds with host defense peptides designed for regenerative endodontics
are desirable nanobiotechnological tools for dentistry. Here, different scaffolds were tested …

[HTML][HTML] Different expression patterns of inflammatory cytokines induced by lipopolysaccharides from Escherichia coli or Porphyromonas gingivalis in human dental …

C Lan, S Chen, S Jiang, H Lei, Z Cai, X Huang - BMC Oral Health, 2022 - Springer
Background Lipopolysaccharide (LPS) is one of the leading causes of pulpitis. The
differences in establishing an in vitro pulpitis model by using different lipopolysaccharides …

[HTML][HTML] In Vitro and In Vivo Anti-Inflammatory Potential of Cannabichromene Isolated from Hemp

M Hong, JH Kim, JH Han, BR Ryu, YS Lim, JD Lim… - Plants, 2023 - mdpi.com
Cannabichromene (CBC), a non-psychoactive cannabinoid found in Cannabis sativa, has
recently been shown to possess several medicinal properties. However, how CBC produces …

[HTML][HTML] Fibroblast membrane-camouflaged nanoparticles for inflammation treatment in the early stage

L Sun, L He, W Wu, L Luo, M Han, Y Liu, S Shi… - International Journal of …, 2021 - nature.com
Unrestrained inflammation is harmful to tissue repair and regeneration. Immune cell
membrane-camouflaged nanoparticles have been proven to show promise as inflammation …

Dual‐Fuel Propelled Nanomotors with Two‐Stage Permeation for Deep Bacterial Infection in the Treatment of Pulpitis

H Wang, X Chen, L Zhang, Z Han, J Zheng… - Advanced …, 2024 - Wiley Online Library
Bacterial infection‐induced inflammatory response could cause irreversible death of pulp
tissue in the absence of timely and effective therapy. Given that, the narrow structure of root …

MicroRNA‐223 negatively regulates LPS‐induced inflammatory responses by targeting NLRP3 in human dental pulp fibroblasts

D Wang, S Sun, Y Xue, J Qiu, T Ye… - International …, 2021 - Wiley Online Library
Aim To investigate the effect of miR‐223 on NLRP3, subsequently regulating the production
of the NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokines IL‐1β …

MicroRNA‐22 suppresses NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokine production by targeting the HIF‐1α and NLRP3 in human …

W Jiang, S Sun, D Wang, J Qiu, Y Song… - International …, 2022 - Wiley Online Library
Aim To investigate the synergetic regulatory effect of miR‐22 on HIF‐1α and NLRP3,
subsequently regulating the production of the NLRP3/CASP1 inflammasome pathway …

[HTML][HTML] Diagnostic biomarker candidates for pulpitis revealed by bioinformatics analysis of merged microarray gene expression datasets

M Chen, J Zeng, Y Yang, B Wu - BMC Oral Health, 2020 - Springer
Background Pulpitis is an inflammatory disease, the grade of which is classified according to
the level of inflammation. Traditional methods of evaluating the status of dental pulp tissue in …