Polymeric nanoparticles: Promising platform for drug delivery

M Khalid, HS El-Sawy - International journal of pharmaceutics, 2017 - Elsevier
Nano medicine had viewed countless breakthroughs in drug delivery implementations. The
main objective of nanotechnology application in delivering and carrying many promising …

Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach

G Mahmoodi Chalbatani, H Dana… - International journal …, 2019 - Taylor & Francis
Cancer is one of the most complex diseases that has resulted in multiple genetic disorders
and cellular abnormalities. Globally, cancer is the most common health concern disease that …

Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy

AD Dey, A Bigham, Y Esmaeili, M Ashrafizadeh… - Seminars in Cancer …, 2022 - Elsevier
Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …

Spontaneous emulsification

C Solans, D Morales, M Homs - Current Opinion in Colloid & Interface …, 2016 - Elsevier
Spontaneous emulsification may occur when immiscible liquids in non-equilibrium
conditions are in contact. This phenomenon is triggered by gradients of chemical potential …

PLGA nanoparticles prepared by nano-emulsion templating using low-energy methods as efficient nanocarriers for drug delivery across the blood–brain barrier

C Fornaguera, A Dols-Pérez, G Calderó… - Journal of Controlled …, 2015 - Elsevier
Neurodegenerative diseases have an increased prevalence and incidence nowadays,
mainly due to aging of the population. In addition, current treatments lack efficacy, mostly …

Nanobiomaterial vectors for improving gene editing and gene therapy

SW Hu, T Ding, H Tang, H Guo, W Cui, Y Shu - Materials Today, 2023 - Elsevier
With the development of genome editing techniques, gene therapy is becoming a viable
option for the treatment of a variety of human diseases. Genome editing techniques mainly …

Nanotechnology in drug and gene delivery

S Hamimed, M Jabberi, A Chatti - Naunyn-schmiedeberg's Archives of …, 2022 - Springer
Over the last decade, nanotechnology has widely addressed many nanomaterials in the
biomedical area with an opportunity to achieve better-targeted delivery, effective treatment …

Interactions of PLGA nanoparticles with blood components: protein adsorption, coagulation, activation of the complement system and hemolysis studies

C Fornaguera, G Calderó, M Mitjans, MP Vinardell… - Nanoscale, 2015 - pubs.rsc.org
The intravenous administration of poly (lactic-co-glycolic) acid (PLGA) nanoparticles has
been widely reported as a promising alternative for delivery of drugs to specific cells …

Carbosilane dendrimers: Drug and gene delivery applications

N Rabiee, S Ahmadvand, S Ahmadi, Y Fatahi… - Journal of Drug Delivery …, 2020 - Elsevier
Carbosilane dendrimers are a particular type of dendrimer structure that has been used as
delivery vehicles for drugs and nucleic acids. They have a defined structure according to …