Intimal sarcoma with MDM2/CDK4 amplification and p16 overexpression: a review of histological features in primary tumor and xenograft, with immunophenotype and …

F Giner, I Machado, LA Rubio-Martínez… - International Journal of …, 2023 - mdpi.com
Intimal sarcomas (IS) are rare malignant mesenchymal tumors arising in large blood vessels
of the systemic and pulmonary circulation and also in the heart. They are morphologically …

[HTML][HTML] Telomere Length and Telomerase Activity as Potential Biomarkers for Gastrointestinal Cancer

C Loukopoulou, T Nikolouzakis, I Koliarakis… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary Cancer affects millions worldwide, with gastrointestinal cancers being
notably common. This review explores the potential of telomeres and telomerase as …

[HTML][HTML] Parental telomeres implications on immune senescence of newborns

S Farrukh, S Baig - American Journal of Clinical and Experimental …, 2023 - ncbi.nlm.nih.gov
Telomere, the biological chronometer, and its effect on the immune system considerably
varies among individuals. During pregnancy, multiple risk factors affect telomere …

A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches

M Iskandar, M Xiao Barbero, M Jaber, R Chen… - Cancers, 2025 - mdpi.com
Background/Objectives: As cells divide, telomeres shorten through a phenomenon known as
telomere attrition, which leads to unavoidable senescence of cells. Unprotected DNA …