Subcutaneous injection of therapeutic monoclonal antibodies (mAbs) has recently attracted unprecedented interests in the pharmaceutical industry. The drug transport in the tissue and …
The Starling principle describes exchanges between blood and tissues based on the balance of hydrostatic and osmotic flows. However, the permeation properties of the main …
Subcutaneous injection for self-administration of biotherapeutics, such as monoclonal antibodies, has emerged as a fast-growing field in the pharmaceutical industry. Effective …
We develop a mathematical model for adsorption based on averaging the flow around, and diffusion inside, adsorbent particles in a column. The model involves three coupled partial …
M Fiori, S Pramanik, CW MacMinn - Journal of Fluid Mechanics, 2023 - cambridge.org
Soft porous materials, such as biological tissues and soils, are exposed to periodic deformations in a variety of natural and industrial contexts. The detailed flow and mechanics …
We study fluid-induced deformation and fracture of cohesive granular media, and apply photoporomechanics to uncover the underpinning grain-scale mechanics. We fabricate …
The present work develops the Poro-Hyperelasticity Theory (P-HT) into a fluid-saturated porous polymeric skeleton under Ogden-Hill material model with inhomogeneous properties …
SL Franco, F Parrinello, G Borino - Computer Methods in Applied …, 2025 - Elsevier
A poroelastic medium is defined as a continuous system in which the mechanical response arises from the interaction between a deformable elastic solid skeleton and a pressurised …
JA Epstein, GZ Ramon - Journal of Colloid and Interface Science, 2024 - Elsevier
Hypothesis The compaction of hydrogel films under permeation flow can be measured, in- situ, by tracking the internal displacements of their structure, therefore revealing the internal …