Soft hydraulics: from Newtonian to complex fluid flows through compliant conduits

IC Christov - Journal of Physics: Condensed Matter, 2021 - iopscience.iop.org
Microfluidic devices manufactured from soft polymeric materials have emerged as a
paradigm for cheap, disposable and easy-to-prototype fluidic platforms for integrating …

Using poro-elasticity to model the large deformation of tissue during subcutaneous injection

Y Leng, M de Lucio, H Gomez - Computer Methods in Applied Mechanics …, 2021 - Elsevier
Subcutaneous injection of therapeutic monoclonal antibodies (mAbs) has recently attracted
unprecedented interests in the pharmaceutical industry. The drug transport in the tissue and …

Asymmetry of tensile versus compressive elasticity and permeability contributes to the regulation of exchanges in collagen gels

J Cacheux, J Ordonez-Miranda, A Bancaud… - Science …, 2023 - science.org
The Starling principle describes exchanges between blood and tissues based on the
balance of hydrostatic and osmotic flows. However, the permeation properties of the main …

Isogeometric analysis of subcutaneous injection of monoclonal antibodies

M de Lucio, M Bures, AM Ardekani, PP Vlachos… - Computer Methods in …, 2021 - Elsevier
Subcutaneous injection for self-administration of biotherapeutics, such as monoclonal
antibodies, has emerged as a fast-growing field in the pharmaceutical industry. Effective …

[HTML][HTML] An analytical investigation into solute transport and sorption via intra-particle diffusion in the dual-porosity limit

LC Auton, M Aguareles, A Valverde, TG Myers… - Applied Mathematical …, 2024 - Elsevier
We develop a mathematical model for adsorption based on averaging the flow around, and
diffusion inside, adsorbent particles in a column. The model involves three coupled partial …

Flow and deformation due to periodic loading in a soft porous material

M Fiori, S Pramanik, CW MacMinn - Journal of Fluid Mechanics, 2023 - cambridge.org
Soft porous materials, such as biological tissues and soils, are exposed to periodic
deformations in a variety of natural and industrial contexts. The detailed flow and mechanics …

Crossover from viscous fingering to fracturing in cohesive wet granular media: a photoporomechanics study

Y Meng, W Li, R Juanes - Soft Matter, 2023 - pubs.rsc.org
We study fluid-induced deformation and fracture of cohesive granular media, and apply
photoporomechanics to uncover the underpinning grain-scale mechanics. We fabricate …

On strain-induced degradation of the polymeric skeleton in poro-hyperelastic inflating vessels by a non-equilibrium thermodynamic framework

M Kazemian, A Hassani, AM Goudarzi - International Journal of …, 2022 - Elsevier
The present work develops the Poro-Hyperelasticity Theory (P-HT) into a fluid-saturated
porous polymeric skeleton under Ogden-Hill material model with inhomogeneous properties …

[HTML][HTML] A variationally-consistent hybrid equilibrium element formulation for linear poroelasticity

SL Franco, F Parrinello, G Borino - Computer Methods in Applied …, 2025 - Elsevier
A poroelastic medium is defined as a continuous system in which the mechanical response
arises from the interaction between a deformable elastic solid skeleton and a pressurised …

In-situ measurement of the internal compaction of a soft material caused by permeation flow

JA Epstein, GZ Ramon - Journal of Colloid and Interface Science, 2024 - Elsevier
Hypothesis The compaction of hydrogel films under permeation flow can be measured, in-
situ, by tracking the internal displacements of their structure, therefore revealing the internal …