[HTML][HTML] Computational fluid dynamics modeling of cell cultures in bioreactors and its potential for cultivated meat production—A mini-review

FJC Rivera, J Chen - Future Foods, 2022 - Elsevier
Cultivated meat production was developed as a response to the rapidly increasing demand
for meat consumption. Bioreactor designs were adapted from other bioprocesses to account …

Engineering 3D micro-compartments for highly efficient and scale-independent expansion of human pluripotent stem cells in bioreactors

PJR Cohen, E Luquet, J Pletenka, A Leonard, E Warter… - Biomaterials, 2023 - Elsevier
Human pluripotent stem cells (hPSCs) have emerged as the most promising cellular source
for cell therapies. To overcome the scale-up limitations of classical 2D culture systems …

[图书][B] Mass production of mesenchymal stem cells—impact of bioreactor design and flow conditions on proliferation and differentiation

V Jossen, R Pörtner, SC Kaiser, M Kraume, D Eibl… - 2014 - books.google.com
Stem cells have enormous potential in health and medical research due to their ability to
differentiate into specialized cells and to self-renew. Applications can be seen in cell-based …

Growth behavior of human adipose tissue-derived stromal/stem cells at small scale: Numerical and experimental investigations

V Jossen, R Eibl, M Kraume, D Eibl - Bioengineering, 2018 - mdpi.com
Human adipose tissue-derived stromal/stem cells (hASCs) are a valuable source of cells for
clinical applications, especially in the field of regenerative medicine. Therefore, it comes as …

Strengthening in hybrid alumina-titanium diboride aluminum matrix composites synthesized by ultrasonic assisted reactive mechanical mixing

AD Moghadam, E Omrani, H Lopez, L Zhou… - Materials Science and …, 2017 - Elsevier
A novel ultrasonic assisted in-situ stir mixing method, in which the reinforcements are
synthesized in liquid aluminum, has been used to fabricate surface clean nano-or submicron …

Physical optimization of cell proliferation and differentiation using spinner flask and microcarriers

F Yang, S Wang, Y Li, S Li, W Liu, Y Li, H Hu - AMB Express, 2022 - Springer
The traditional breeding industry has been increasingly saturated and caused
environmental pollution, disease transmission, excessive resource use, and methane …

Stem cells culture bioreactor fluid flow, shear stress and microcarriers dispersion analysis using computational fluid dynamics

M Julaey, M Hosseini, H Amani - Journal of Applied Biotechnology …, 2016 - biotechrep.ir
The growth rate of stem cells in Mobius CellReady 3L bioreactor has been studied using
COMSOL Multi-physics simulation software in order to find out the best operational …

The disc-shaped microcarriers: a new tool for increasing harvesting of adipose-derived mesenchymal stromal cells

T Le Clainche, A Moisan, JL Coll… - Biochemical Engineering …, 2021 - Elsevier
Human adipose-derived mesenchymal stromal cells (A-MSC) are promising tools for
regenerative medicine, but their in vitro amplification before administration is still an issue …

C-Stem: Engineering Niche-Like Micro-Compartments for Optimal and Scale-Independent Expansion of Human Pluripotent Stem Cells in Bioreactors

PJR Cohen, E Luquet, J Pletenka, A Leonard, E Warter… - BioRXiv, 2021 - biorxiv.org
Human pluripotent stem cells (hPSCs) have emerged as the most promising cellular source
for cell therapies. To overcome scale up limitations of classical 2D culture systems …

Encapsulation de cellules souches pluripotentes pour développer et produire à l'échelle des thérapies cellulaires biomimétiques

P Cohen - 2022 - theses.hal.science
Les thérapies cellulaires suscitent l'espoir de millions de patients souffrant de maladies
chroniques ou en impasse thérapeutique. Les cellules souches pluripotentes en constituent …