Pulmonary alveolar proteinosis is a rare clinical syndrome that was first described in 1958.
Subsequently, over 240 case reports and small series have described at least 410 cases in …

Pulmonary surfactants consist of phospholipids and the hydrophobic proteins surfactant
protein B and surfactant protein C. These surfactants keep the alveoli in the lung open to the …

Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Advances in physiology and biochemistry have provided fundamental insights into the role
of pulmonary surfactant in the pathogenesis and treatment of preterm infants with respiratory …

Lysophosphatidylcholine (LPC) and lysophosphatidic acid (LPA), the most prominent
lysoglycerophospholipids, are emerging as a novel class of inflammatory lipids, joining …

Pulmonary surfactant is a lipid/protein complex synthesized by the alveolar epithelium and
secreted into the airspaces, where it coats and protects the large respiratory air–liquid …

Mutations in the genes encoding the surfactant proteins B and C (SP-B and SP-C) and the
phospholipid transporter, ABCA3, are associated with respiratory distress and interstitial …

▪ Abstract The hydrophobic surfactant proteins, SP-B and SP-C, have important roles in
surfactant function. The importance of these proteins in normal lung function is highlighted …

Genes involved in the production of pulmonary surfactant are crucial for the development
and maintenance of healthy lungs. Germline mutations in surfactant-related genes cause a …

Interstitial lung disease (ILD) in infants and children comprises a large spectrum of rare
respiratory disorders that are mostly chronic and associated with high morbidity and …