Neurotoxic agent-induced injury in neurodegenerative disease model: Focus on involvement of glutamate receptors
Glutamate receptors play a crucial role in the central nervous system and are implicated in
different brain disorders. They play a significant role in the pathogenesis of …
different brain disorders. They play a significant role in the pathogenesis of …
Therapeutic Potential of Sodium Channel Blockers as a Targeted Therapy Approach in KCNA1-Associated Episodic Ataxia and a Comprehensive Review of the …
S Lauxmann, L Sonnenberg, NA Koch… - Frontiers in …, 2021 - frontiersin.org
Introduction: Among genetic paroxysmal movement disorders, variants in ion channel
coding genes constitute a major subgroup. Loss-of-function (LOF) variants in KCNA1, the …
coding genes constitute a major subgroup. Loss-of-function (LOF) variants in KCNA1, the …
3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary
nucleus (ION) in the brain stem. Although several studies have explored the effect of this …
nucleus (ION) in the brain stem. Although several studies have explored the effect of this …
[HTML][HTML] Contribution of somatic and dendritic SK channels in the firing rate of Deep Cerebellar Nuclei: Implication in cerebellar ataxia
Methods: In this study, multi-compartment computational model of DCN was used. This
computational stimulation allowed us to study the changes in the firing activity of DCN …
computational stimulation allowed us to study the changes in the firing activity of DCN …
Towards a therapeutic intervention in polyglutamine ataxias: from models to clinical trials
N Kazachkova, M Lima - Front Clin Res-CNS Neurolog Disord, 2015 - books.google.com
The autosomal dominant (AD) forms of hereditary ataxias compose a heterogeneous group
of diseases, in which cerebellar degeneration and dysfunction is consistently present …
of diseases, in which cerebellar degeneration and dysfunction is consistently present …
Riluzole in Progressive Cerebellar Ataxias
S Romano, C Romano, E Morena, F Troili… - Trials for Cerebellar …, 2023 - Springer
Converging experimental data suggested attempts of using in human beings modulator of
ion channels to counteract the neurodegenerative process in progressive cerebellar ataxia …
ion channels to counteract the neurodegenerative process in progressive cerebellar ataxia …
Riluzole in Progressive Cerebellar Ataxias Silvia Romano, Carmela Romano, Emanuele Morena, Fernanda Troili, Agnese Suppiej, Marco Salvetti, and Giovanni …
S Romano - Trials for Cerebellar Ataxias: From Cellular Models …, 2023 - books.google.com
Converging experimental data suggested attempts of using in human beings modulator of
ion channels to counteract the neurodegenerative process in progressive cerebellar ataxia …
ion channels to counteract the neurodegenerative process in progressive cerebellar ataxia …