Materials design for bone-tissue engineering

GL Koons, M Diba, AG Mikos - Nature Reviews Materials, 2020 - nature.com
Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Effect of the nano/microscale structure of biomaterial scaffolds on bone regeneration

L Zhu, D Luo, Y Liu - International Journal of Oral Science, 2020 - nature.com
Natural bone is a mineralized biological material, which serves a supportive and protective
framework for the body, stores minerals for metabolism, and produces blood cells nourishing …

Scaffolds for bone-tissue engineering

SS Lee, X Du, I Kim, SJ Ferguson - Matter, 2022 - cell.com
Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

[HTML][HTML] Biomaterial-induced pathway modulation for bone regeneration

S Vermeulen, ZT Birgani, P Habibovic - Biomaterials, 2022 - Elsevier
Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …

Bioceramics to regulate stem cells and their microenvironment for tissue regeneration

Y Zhou, C Wu, J Chang - Materials Today, 2019 - Elsevier
Bioceramics have been used for the replacement and repair of damaged hard tissues for
about 50 years, in which the mechanical properties and biocompatibility of the materials are …

A tough injectable self‐setting cement‐based hydrogel for noninvasive bone augmentation

P Jin, M Xia, M Hasany, P Feng, J Bai… - Interdisciplinary …, 2023 - Wiley Online Library
Composite hydrogels with excellent properties can open new opportunities to terminate the
need for auto/allografts in bone augmentations. However, their clinical application has been …

A unique biomimetic modification endows polyetherketoneketone scaffold with osteoinductivity by activating cAMP/PKA signaling pathway

B Yuan, Y Zhang, R Zhao, H Lin, X Yang, X Zhu… - Science …, 2022 - science.org
Osteoinductivity of a biomaterial scaffold can notably enhance the bone healing
performance. In this study, we developed a biomimetic and hierarchically porous …

Bone regeneration with micro/nano hybrid-structured biphasic calcium phosphate bioceramics at segmental bone defect and the induced immunoregulation of MSCs

Y Zhu, K Zhang, R Zhao, X Ye, X Chen, Z Xiao, X Yang… - Biomaterials, 2017 - Elsevier
Adequate bone regeneration has been difficult to achieve at segmental bone defects caused
by disease. The surface structure and phase composition of calcium phosphate bioceramic …

Creating hierarchical porosity hydroxyapatite scaffolds with osteoinduction by three-dimensional printing and microwave sintering

X Pei, L Ma, B Zhang, J Sun, Y Sun, Y Fan, Z Gou… - …, 2017 - iopscience.iop.org
Hierarchical porosity, which includes micropores and macropores in scaffolds, contributes to
important multiple biological functions for tissue regeneration. This paper introduces a two …