Abstract The One Health concept promotes integrated evaluation of human, animal, and
environmental health questions to expedite advances benefiting all species. A recognition of …

Tumorigenesis and metastasis have deep connections to inflammation and inflammatory
cytokines, but the mechanisms underlying these relationships are poorly understood …

Hair growth can be induced from resting mouse hair follicles by topical application of JAK
inhibitors, suggesting that JAK-STAT signaling is required for maintaining hair follicle stem …

Mammary gland development occurs mainly after birth and is composed of three successive
stages: puberty, pregnancy and lactation, and involution. These developmental stages are …

Under normal conditions, the most significant expansion and differentiation of the adult
mammary gland occurs in response to systemic reproductive hormones during pregnancy …

Since seminal descriptions of signal transducer and activator of transcription 3 (STAT3) as a
signal transducer and transcriptional regulator, which is most usually activated by …

Cancer is the disease with highest public health impact in developed countries. Particularly,
breast cancer has the highest incidence in women worldwide and the fifth highest mortality …

The GATA-type zinc finger transcription factor TRPS1 has been implicated in breast cancer.
However, its precise role remains unclear, as both amplifications and inactivating mutations …

Sheep, cows, cats, and rabbits are kept by humans for agricultural purposes and as
companion animals. Much of the mammary research in these species has focussed on …

The signal transducer and activator of transcription (STAT) are transcription factors that work
via JAK/STAT pathway regulating the expression of genes involved in cell survival …