Messenger RNA (mRNA) localization allows spatiotemporal regulation of the proteome at
the subcellular level. This is observed in the axons of neurons, where mRNA localization is …

The presence of activin A and its effects have previously been documented in the adrenal
gland, particularly in the human fetal adrenal gland and the rat adrenal gland. The primary …

Cancer-associated cachexia (CAC) is a hypermetabolic syndrome characterized by
unintended weight loss due to the atrophy of adipose tissue and skeletal muscle. A …

Satellite glia are the major glial cells in sympathetic ganglia, enveloping neuronal cell
bodies. Despite this intimate association, the extent to which sympathetic functions are …

Midbrain dopaminergic (mDA) neurons exhibit extensive dendritic and axonal arborizations,
but local protein synthesis is not characterized in these neurons. Here, we investigate …

Skeletal diseases and their surgical treatment induce severe pain. The innervation density of
bone potentially explains the severe pain reported. Animal studies concluded that sensory …

Objectives Recent commercialization of methods for in situ hybridization using Z-pair
probe/branched DNA amplification has led to increasing adoption of this technology for …

Olfactory behavior is important for animal survival, and olfactory dysfunction is a common
feature of several diseases. Despite the identification of neural circuits and circulating …

ABSTRACT RNA localization to neuronal dendrites and axons is increasingly recognized as
a significant and widespread mechanism of gene expression control in neurons. High …

Intra-axonal protein synthesis has been shown to play critical roles in both development and
repair of axons. Axons provide long-range connectivity in the nervous system, and disruption …