Purpose The failure in timely healing of wounds is a central feature in chronic wounds that
leads to physiological, psychological and economic burdens. Macrophages have been …

A diabetic foot ulcer (DFU) is one of the major complications of diabetes. Wound healing
under diabetic conditions is often impaired. This is in part due to the excessive oxidative …

We postulate that nanoparticles (NPs) for use in therapeutic applications have largely not
realized their clinical potential due to an overall inability to use in vitro results to predict NP …

A large number of models are now available for the investigation of skin wound healing.
These can be used to study the processes that take place in a phase-specific manner under …

Biofilm-associated infections (BAI) have posed serious threats to public health. Novel
therapy based on carbon monoxide (CO) is being increasingly appreciated. However, CO …

Venomous snake bite adversely affects millions of people yearly, but few animal models
allow for the determination of toxicodynamic timelines with hemotoxic venoms to …

Carbon monoxide-releasing molecules (CO-RMs) are a class of organometallo compounds
capable of delivering controlled quantities of CO gas to cells and tissues thus exerting a …

Carbon monoxide (CO) is a gaseous signaling molecule that modulates inflammation, cell
survival, and recovery after myocardial infarction. However, handling and dosing of CO as a …

Tissue repair is often impaired in pathological states, highlighting the need for innovative
wound-healing technologies. This study introduces composite hyaluronic acid gas …

Clinical incidences of pressure ulcers in the elderly and intractable skin ulcers in diabetic
patients are increasing because of the aging population and an increase in the number of …