Advances in the prevention and treatment of breast cancer-related lymphedema

PMC Donahue, A MacKenzie, A Filipovic… - Breast cancer research …, 2023 - Springer
Purpose Breast cancer-related lymphedema (BCRL) represents a lifelong risk for breast
cancer survivors and once acquired becomes a lifelong burden. This review summarizes …

Lymphedema: pathogenesis and novel therapies

JH Dayan, CL Ly, RP Kataru… - Annual review of …, 2018 - annualreviews.org
Lymphedema affects up to 1 in 6 patients who undergo treatment for a solid tumor in the
United States. Its prevalence has increased as more effective oncologic therapies have …

Breast surgery: management of postoperative complications following operations for breast cancer

Z Al-Hilli, A Wilkerson - Surgical Clinics, 2021 - surgical.theclinics.com
Breast cancer is the most common cancer diagnosed among women in the Unites States
and globally. 1 The American Cancer Society has estimated that 333,490 new cases of …

The effect of prophylactic lymphovenous anastomosis and shunts for preventing cancer‐related lymphedema: A systematic review and meta‐analysis

MG Jørgensen, NM Toyserkani, JA Sørensen - Microsurgery, 2018 - Wiley Online Library
Background Lymphedema is one of the most dreaded side effects to any cancer treatment
involving lymphadenectomy. Progressed lymphedema is adversely complex and currently …

[HTML][HTML] Phase 1 LymfactinⓇ Study: short-term safety of combined adenoviral VEGF-C and lymph node transfer treatment for upper extremity lymphedema

P Hartiala, S Suominen, E Suominen… - Journal of Plastic …, 2020 - Elsevier
Objective To study the safety and tolerability of LymfactinⓇ treatment combined with
microvascular lymph node transfer surgery in patients with upper limb lymphedema …

[HTML][HTML] Phase 1 Lymfactin® study: 24-month efficacy and safety results of combined adenoviral VEGF-C and lymph node transfer treatment for upper extremity …

IM Leppäpuska, P Hartiala, S Suominen… - Journal of Plastic …, 2022 - Elsevier
ABSTRACT BACKGROUND Lymphedema is a common problem after breast cancer
treatment. Lymfactin® is a prolymphangiogenic growth factor vector inducing the expression …

Supermicrosurgery: principles and applications

JP Hong, S Song, HSP Suh - Journal of surgical oncology, 2018 - Wiley Online Library
Supermicrosurgery is defined as microsurgery in less than 0.8 mm vessels. It is an evolved
form of microsurgery but with the same principle:(1) enhanced working environment …

Combined lymph node transfer and suction‐assisted lipectomy in lymphedema treatment: A prospective study

A Bolletta, G di Taranto, L Losco, R Elia, G Sert… - …, 2022 - Wiley Online Library
Background Recent studies have analyzed the combination of suction‐assisted lipectomy
(SAL) and vascularized lymph node transfer (VLNT) in lymphedema treatment, reporting …

Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective

S Jt, B WAM, B AC, N SA - Journal of Molecular Medicine, 2022 - Springer
Despite the development of novel pharmacological treatments, cardiovascular disease
morbidity and mortality remain high indicating an unmet clinical need. Viral gene therapy …

A prospective study on the safety and efficacy of vascularized lymph node transplant

S Brown, BJ Mehrara, M Coriddi, L McGrath… - Annals of …, 2022 - journals.lww.com
Purpose: While vascularized lymph node transplant (VLNT) has gained popularity, there are
a lack of prospective long-term studies and standardized outcomes. The purpose of this …