Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Insects are infected by a wide array of viruses some of which are insect restricted and
pathogenic, and some of which are transmitted by biting insects to vertebrates. The medical …

The discovery of small noncoding RNAs (sncRNAs) with regulatory functions is a recent
breakthrough in biology. Among sncRNAs, microRNA (miRNA), derived from host or virus …

Deep sequencing studies frequently identify small RNA fragments of abundant RNAs. These
fragments are thought to represent degradation products of their precursors. Using …

Aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the
infection. We examine a piRNA-based immunity that relies on the acquisition of viral derived …

The natural maintenance cycles of many mosquito-borne pathogens require establishment
of persistent non-lethal infections in the invertebrate host. The mechanism by which this …

Ticks are ectoparasitic arthropods that necessarily feed on the blood of their vertebrate
hosts. The success of blood acquisition depends on the pharmacological properties of tick …

Highlights•RNAi is an important antiviral defense mechanism in insects.•All major classes of
viruses are targets of the antiviral RNAi response.•Viruses encode suppressors that interfere …

Understanding the diversity and consequences of viruses present in honey bees is critical
for maintaining pollinator health and managing the spread of disease. The viral landscape of …

Mosquito-borne viral diseases are a major concern of global health and result in significant
economic losses in many countries. As natural vectors, mosquitoes are very permissive to …