A review on synthetic chalcone derivatives as tubulin polymerisation inhibitors

W Liu, M He, Y Li, Z Peng, G Wang - Journal of enzyme inhibition …, 2022 - Taylor & Francis
Microtubules play an important role in the process of cell mitosis and can form a spindle in
the mitotic prophase of the cell, which can pull chromosomes to the ends of the cell and then …

Recent progress in synthesis and characterization of metal chalcone complexes and their potential as bioactive agents

C Sulpizio, J Breibeck, A Rompel - Coordination Chemistry Reviews, 2018 - Elsevier
This review presents an overview on the synthesis, characterization and applications of
metal complexes containing chalcone (1, 3-diphenylprop-2-en-1-one) and its derivatives as …

Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by …

G Wang, W Liu, Z Gong, Y Huang, Y Li… - Journal of enzyme …, 2020 - Taylor & Francis
A series of naphthalene-chalcone derivatives (3a–3t) were prepared and evaluated as
tubulin polymerisation inhibitor for the treatment of breast cancer. All compounds were …

Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin

K Sun, Z Sun, F Zhao, G Shan… - Future Medicinal Chemistry, 2021 - Taylor & Francis
Microtubules have been a concerning target of cancer chemotherapeutics for decades, and
several tubulin-targeted agents, such as paclitaxel, vincristine and vinorelbine, have been …

Thiocarbamate-Directed Tandem Olefination–Intramolecular Sulfuration of Two Ortho C–H Bonds: Application to Synthesis of a COX-2 Inhibitor

W Li, Y Zhao, S Mai, Q Song - Organic letters, 2018 - ACS Publications
A palladium-catalyzed dual ortho C–H bond activation of aryl thiocarbamates is developed.
This tandem reaction initiates by thiocarbamate-directed ortho C–H palladation, which leads …

1, 3-dioxoles and 1, 3-oxathioles

RA Aitken - … heterocyclic chemistry IV: a review of …, 2021 - research-portal.st-andrews.ac.uk
Developments in the chemistry of five-membered ring heterocycles containing two non-
adjacent oxygens or one oxygen and one sulfur in the period 2008–2020 are reviewed …

Five-Membered Ring Systems: With O and S (Se, Te) Atoms

RA Aitken - Progress in Heterocyclic Chemistry, 2017 - Elsevier
Five-Membered Ring Systems: With O and S (Se, Te) Atoms - ScienceDirect Skip to main
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