Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Designing self-healing hydrogels for biomedical applications

X Ding, L Fan, L Wang, M Zhou, Y Wang, Y Zhao - Materials Horizons, 2023 - pubs.rsc.org
Self-healing hydrogels have emerged as the most promising alternatives to conventional
brittle hydrogels used in the biomedical field due to the features of long-term stability and …

3D bioprinting of cell‐laden hydrogels for improved biological functionality

SM Hull, LG Brunel, SC Heilshorn - Advanced Materials, 2022 - Wiley Online Library
The encapsulation of cells within gel‐phase materials to form bioinks offers distinct
advantages for next‐generation 3D bioprinting. 3D bioprinting has emerged as a promising …

Dynamic covalent hydrogels as biomaterials to mimic the viscoelasticity of soft tissues

S Tang, BM Richardson, KS Anseth - Progress in Materials Science, 2021 - Elsevier
The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …

Bioprinting: From Tissue and Organ Development to in Vitro Models

C Mota, S Camarero-Espinosa, MB Baker… - Chemical …, 2020 - ACS Publications
Bioprinting techniques have been flourishing in the field of biofabrication with pronounced
and exponential developments in the past years. Novel biomaterial inks used for the …

Dynamic covalent bonds in self-healing, shape memory, and controllable stiffness hydrogels

MM Perera, N Ayres - Polymer Chemistry, 2020 - pubs.rsc.org
Emerging technologies are increasingly reliant on materials that deliver multiple
functionality. For example, hydrogels using dynamic covalent crosslinks have proven well …

Dynamic bioinks to advance bioprinting

FLC Morgan, L Moroni, MB Baker - Advanced healthcare …, 2020 - Wiley Online Library
The development of bioinks for bioprinting of cell‐laden constructs remains a challenge for
tissue engineering, despite vigorous investigation. Hydrogels to be used as bioinks must …

Varying PEG density to control stress relaxation in alginate-PEG hydrogels for 3D cell culture studies

S Nam, R Stowers, J Lou, Y Xia, O Chaudhuri - Biomaterials, 2019 - Elsevier
Hydrogels are commonly used as artificial extracellular matrices for 3D cell culture and for
tissue engineering. Viscoelastic hydrogels with tunable stress relaxation have recently been …