Self‐assembling peptide‐based hydrogels for wound tissue repair

T Guan, J Li, C Chen, Y Liu - Advanced Science, 2022 - Wiley Online Library
Wound healing is a long‐term, multistage biological process that includes hemostasis,
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …

Cell death mediated by the pyroptosis pathway with the aid of nanotechnology: prospects for cancer therapy

D Wu, S Wang, G Yu, X Chen - Angewandte Chemie, 2021 - Wiley Online Library
Pyroptosis, a unique form of programmed cell death (PCD) that is characterized by DNA
fragmentation, chromatin condensation, cellular swelling with big bubbles, and leakage of …

Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop

T Xu, J Wang, S Zhao, D Chen, H Zhang… - Nature …, 2023 - nature.com
The amino acid sequences of peptides determine their self-assembling properties. Accurate
prediction of peptidic hydrogel formation, however, remains a challenging task. This work …

Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma

F Wang, Q Huang, H Su, M Sun… - Proceedings of the …, 2023 - National Acad Sciences
The unique cancer-associated immunosuppression in brain, combined with a paucity of
infiltrating T cells, contributes to the low response rate and poor treatment outcomes of T cell …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Supramolecular filament hydrogel as a universal immunomodulator carrier for immunotherapy combinations

F Wang, H Su, Z Wang, CF Anderson, X Sun, H Wang… - ACS …, 2023 - ACS Publications
A major challenge of cancer immunotherapy is to develop delivery strategies that can
effectively and safely augment the immune system's antitumor response. Here, we report on …

Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

Y Wang, J Zhan, J Huang, X Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure
formation or reversible decomposition from building blocks. This process is driven by non …

Self-assembling hydrogel structures for neural tissue repair

S Peressotti, GE Koehl, JA Goding… - … Biomaterials Science & …, 2021 - ACS Publications
Hydrogel materials have been employed as biological scaffolds for tissue regeneration
across a wide range of applications. Their versatility and biomimetic properties make them …

Rational design of peptide-based smart hydrogels for therapeutic applications

S Das, D Das - Frontiers in Chemistry, 2021 - frontiersin.org
Peptide-based hydrogels have captivated remarkable attention in recent times and serve as
an excellent platform for biomedical applications owing to the impressive amalgamation of …

Tumor microenvironment-oriented adaptive nanodrugs based on peptide self-assembly

S Li, W Zhang, H Xue, R Xing, X Yan - Chemical Science, 2020 - pubs.rsc.org
The aberrant metabolism of tumor cells creates an inimitable microenvironment featuring
acidic pH, high glutathione (GSH) levels, and overexpression of certain enzymes, which …