Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

[HTML][HTML] Lymphatic vessel network structure and physiology

JW Breslin, Y Yang, JP Scallan, RS Sweat… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation

D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer

Q Zhang, S Liu, H Wang, K Xiao, J Lu… - Advanced …, 2023 - Wiley Online Library
As a key step of tumor lymphatic metastasis, lymphangiogenesis is regulated by VEGFC‐
VEGFR3 signaling pathway mediated by immune cells, mainly macrophages, in the tumor …

The inflammatory speech of fibroblasts

R Schuster, JS Rockel, M Kapoor… - Immunological …, 2021 - Wiley Online Library
Activation of fibroblasts is a key event during normal tissue repair after injury and the
dysregulated repair processes that result in organ fibrosis. To most researchers, fibroblasts …

Mechanisms regulating skin immunity and inflammation

M Pasparakis, I Haase, FO Nestle - Nature reviews immunology, 2014 - nature.com
Immune responses in the skin are important for host defence against pathogenic
microorganisms. However, dysregulated immune reactions can cause chronic inflammatory …

Cardiac lymphatics are heterogeneous in origin and respond to injury

L Klotz, S Norman, JM Vieira, M Masters, M Rohling… - Nature, 2015 - nature.com
The lymphatic vasculature is a blind-ended network crucial for tissue-fluid homeostasis,
immune surveillance and lipid absorption from the gut. Recent evidence has proposed an …

Lymphatic endothelial cells of the lymph node

S Jalkanen, M Salmi - Nature Reviews Immunology, 2020 - nature.com
The influx and efflux of cells and antigens to and from the draining lymph nodes largely take
place through the subcapsular, cortical and medullary sinus systems. Recent analyses in …

Inflammation and lymphatic function

S Schwager, M Detmar - Frontiers in immunology, 2019 - frontiersin.org
The lymphatic vasculature plays a crucial role in regulating the inflammatory response by
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …

The lymphatic vasculature in disease

K Alitalo - Nature medicine, 2011 - nature.com
Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way
conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic …