Importance Acute appendicitis is the most common abdominal surgical emergency in the
world, with an annual incidence of 96.5 to 100 cases per 100 000 adults. Observations The …

Background and aims Acute appendicitis (AA) is among the most common causes of acute
abdominal pain. Diagnosis of AA is still challenging and some controversies on its …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to infection. In this context, biomarkers could be considered as indicators of either …

Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of …

Evidence-based guidelines for implementation and measurement of antibiotic stewardship
interventions in inpatient populations including long-term care were prepared by a …

Background Gram-negative bacteremia is a major cause of morbidity and mortality in
hospitalized patients. Data to guide the duration of antibiotic therapy are limited. Methods …

Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in the emergency departments worldwide. The …

Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …