1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …

In this review we summarize the impact of bolus versus daily dosing of vitamin D on 25 (OH)
D and 1, 25 (OH) 2D levels, as well as on key countervailing factors that block vitamin D …

1α, 25-Dihydroxyvitamin D3 [1, 25-(OH) 2D3], the active metabolite of vitamin D3, is known
for the maintenance of mineral homeostasis and normal skeletal architecture. However …

Calcitriol (1, 25-dihydroxyvitamin D3), the biologically most active form of vitamin D,
maintains calcium homeostasis through its actions in intestine, bone, kidneys, and the …

Oral cancer is known as one of the most common cancers, with a poor prognosis, related to
delayed clinical diagnosis, either due to the lack of particular biomarkers related to the …

In the last two decades vitamin D (VD) research has demonstrated new extraskeletal actions
of this pre-hormone, suggesting a protective role of this secosteroid in the onset, progression …

Ultraviolet B (UVB), in addition to having carcinogenic activity, is required for the production
of vitamin D3 (D3) in the skin which supplies> 90% of the body's requirement. Vitamin D is …

Abstract The nuclear hormone 1α, 25-dihydroxyvitamin D3 induces cell cycle arrest,
differentiation, or apoptosis depending on target cell type and state. Although the …

Background: Knowledge gaps have contributed to considerable variation among
international dietary recommendations for vitamin D. Objective: We aimed to establish the …