Critical signaling pathways governing hepatocellular carcinoma behavior; small molecule-based approaches

Z Farzaneh, M Vosough, T Agarwal… - Cancer cell international, 2021 - Springer
Hepatocellular carcinoma (HCC) is the second leading cause of death due to cancer.
Although there are different treatment options, these strategies are not efficient in terms of …

Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma

A Hatawsh, RH Al-Haddad, UG Okafor, LM Diab… - Medical Oncology, 2024 - Springer
Hepatocellular carcinoma (HCC) is a leading liver cancer that significantly impacts global
life expectancy and remains challenging to treat due to often late diagnoses. Despite …

Dynamics of m6A RNA methylome on the hallmarks of hepatocellular carcinoma

E Sivasudhan, N Blake, ZL Lu, J Meng… - Frontiers in Cell and …, 2021 - frontiersin.org
Epidemiological data consistently rank hepatocellular carcinoma (HCC) as one of the
leading causes of cancer-related deaths worldwide, often posing severe economic burden …

[HTML][HTML] Updates on the diagnosis and management of hepatocellular carcinoma

A Raees, M Kamran, H Özkan… - Euroasian journal of …, 2021 - ncbi.nlm.nih.gov
Introduction: Globally, the incidence, as well as mortality, related to hepatocellular
carcinoma (HCC) is on the rise, owing to relatively few curative options. Underlying cirrhosis …

The prominence of potential biomarkers in the diagnosis and management of hepatocellular carcinoma: current scenario and future anticipation

IH Mir, KC Jyothi… - Journal of Cellular …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most aggressive and truculent types of
cancer. Early detection of HCC is a massive concern that can boost the overall survival rates …

Research progress for RNA modifications in physiological and pathological angiogenesis

HM Chen, H Li, MX Lin, WJ Fan, Y Zhang, YT Lin… - Frontiers in …, 2022 - frontiersin.org
As a critical layer of epigenetics, RNA modifications demonstrate various molecular
functions and participate in numerous biological processes. RNA modifications have been …

[HTML][HTML] Vascular Endothelial Growth Factor (VEGF) in Liver Disease

D Darmadi, RH Ruslie, C Pakpahan - Tumor Angiogenesis and …, 2022 - intechopen.com
Vascular endothelial growth factor (VEGF) is the most potent stimulating factor for
angiogenesis. Its expression is related to inflammation and hypoxia. In normal conditions …

Vascular endothelial growth factor in relation to the development of hepatocellular carcinoma in hepatitis C virus patients treated by direct-acting antivirals

AM ElGhandour, EM Bayoumy, WA Ibrahim… - Egyptian Liver …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) comprises 5.6% of all cancers worldwide
representing the sixth most common cancer. It is also the fourth most common cause of …

Biomarkers for Hepatocellular Carcinoma− An Updated Review

R Tekupalli, S Anand… - Critical Reviews™ in …, 2021 - dl.begellhouse.com
Hepatocellular carcinoma (HCC) stands third among cancer-related deaths globally. Owing
to its high incidence and linked mortality, early diagnosis is alarming for patient survival and …

The potential role of Vascular Endothelial Growth Factor for hepatocellular carcinoma screening: a systematic review

R Masadah, A Qanitha, R Hanifah, MA Al Atsari… - …, 2024 - f1000research.com
Background Hepatocellular Carcinoma (HCC) stands as the third most fatal malignancy
worldwide, accounting for over 830,000 fatalities annually. This pressing concern has …