COVID-19 pneumonia: pathophysiology and management
L Gattinoni, S Gattarello, I Steinberg… - European …, 2021 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on
the development of its pathophysiologic characteristics over time, and how these time …
the development of its pathophysiologic characteristics over time, and how these time …
SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19
Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to
severe acute respiratory distress. The severity of the illness can also extend from mild …
severe acute respiratory distress. The severity of the illness can also extend from mild …
[HTML][HTML] COVID-19 pneumonia: different respiratory treatments for different phenotypes?
L Gattinoni, D Chiumello, P Caironi, M Busana… - Intensive care …, 2020 - Springer
The Surviving Sepsis Campaign panel recently recommended that “mechanically ventilated
patients with COVID-19 should be managed similarly to other patients with acute respiratory …
patients with COVID-19 should be managed similarly to other patients with acute respiratory …
[HTML][HTML] COVID-19 pneumonia: ARDS or not?
L Gattinoni, D Chiumello, S Rossi - Critical care, 2020 - Springer
Even though it can meet the ARDS Berlin definition [1, 2], the COVID-19 pneumonia is a
specific disease with peculiar phenotypes. Its main characteristic is the dissociation between …
specific disease with peculiar phenotypes. Its main characteristic is the dissociation between …
[HTML][HTML] Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study
P Sinha, KL Delucchi, BT Thompson, DF McAuley… - Intensive care …, 2018 - Springer
Purpose Using latent class analysis (LCA), we have consistently identified two distinct
subphenotypes in four randomized controlled trial cohorts of ARDS. One subphenotype has …
subphenotypes in four randomized controlled trial cohorts of ARDS. One subphenotype has …
Timing of intubation and mortality among critically ill coronavirus disease 2019 patients: a single-center cohort study
AC Hernandez-Romieu, MW Adelman… - Critical care …, 2020 - journals.lww.com
Objectives: Increasing time to mechanical ventilation and high-flow nasal cannula use may
be associated with mortality in coronavirus disease 2019. We examined the impact of time to …
be associated with mortality in coronavirus disease 2019. We examined the impact of time to …
[HTML][HTML] Effect of mechanical power on intensive care mortality in ARDS patients
S Coppola, A Caccioppola, S Froio, P Formenti… - Critical Care, 2020 - Springer
Background In ARDS patients, mechanical ventilation should minimize ventilator-induced
lung injury. The mechanical power which is the energy per unit time released to the …
lung injury. The mechanical power which is the energy per unit time released to the …
Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure
C Brusasco, F Corradi, A Di Domenico… - European …, 2021 - Eur Respiratory Soc
Noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) are
recommended for acute hypoxaemic respiratory failure (AHRF) due to cardiogenic …
recommended for acute hypoxaemic respiratory failure (AHRF) due to cardiogenic …
[HTML][HTML] Prone positioning in acute respiratory distress syndrome
L Gattinoni, M Busana, L Giosa… - … in respiratory and …, 2019 - thieme-connect.com
Prone positioning is nowadays considered as one of the most effective strategies for patients
with severe acute respiratory distress syndrome (ARDS). The evolution of the …
with severe acute respiratory distress syndrome (ARDS). The evolution of the …
High-flow nasal oxygen for severe hypoxemia: oxygenation response and outcome in patients with COVID-19
Rationale: The “Berlin definition” of acute respiratory distress syndrome (ARDS) does not
allow inclusion of patients receiving high-flow nasal oxygen (HFNO). However, several …
allow inclusion of patients receiving high-flow nasal oxygen (HFNO). However, several …